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ProteomicsDeorphanization of neuropeptide GPCRs in Nematostella vectensis
The aim of this part of the wider project is to identify neuropeptide precursors, investigate cleavage sites on neuropeptide precursors and predict mature peptides in the sea anemone Nematostella vectensis. This was done to create a synthetic library of N. vectensis neuropeptides which were then use...
ORGANISM(S): Nematostella vectensis 
2024-04-08 | PXD041235 | Pride
Deorphanization Gpcrs Cleavage sites Cnidaria Neuropeptides Nematostella Precursors 
ProteomicsMass spectrometric evidence for neuropeptide-amidating enzymes in C. elegans
Neuropeptides constitute a vast and functionally diverse family of neurochemical signaling molecules, and are widely involved in the regulation of various physiological processes. The nematode C. elegans is well-suited for the study of neuropeptide biochemistry and function, as neuropeptide biosynth...
ORGANISM(S): Caenorhabditis elegans 
2018-03-12 | PXD008942 | Pride
Peptidomics  mass spectrometry  neuropeptide  amidation  copper monooxygenase  phm  pal  pam  caenorhabditis elegans  lc-orbitrap ms 
UnknownTranscriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution.
Not available
S-EPMC4772807 | biostudies-literature
UnknownEvolution of Neuropeptide Precursors in Polyneoptera (Insecta).
Not available
S-EPMC7179676 | biostudies-literature
ProteomicsNeuropeptidomic Analysis of the Stick Insect, Carausius morosus
One of the most thoroughly studied insect species, with respect to locomotion behaviour, is the stick insect Carausius morosus. Although detailed information exists on premotor networks controlling walking, surprisingly little is known about neuropeptides, which are certainly involved in motor activ...
ORGANISM(S): Carausius morosus 
2018-04-30 | PXD009536 | Pride
Peptidomics Stick insects Mass spectrometry Neurohormones Nervous system Neuropeptide precursors Carausius morosus 
UnknownNeuropeptide precursors in Tribolium castaneum.
Not available
S-EPMC1959474 | biostudies-literature
UnknownNeuropeptide precursors and neuropeptides in the sea cucumber Apostichopus japonicus: a genomic, transcriptomic and proteomic analysis.
Not available
S-EPMC6586643 | biostudies-literature
UnknownNeuroPID: a classifier of neuropeptide precursors.
Not available
S-EPMC4086121 | biostudies-literature
ProteomicsGlobal Spinal Cord Peptidome Profiling in Response to Osteoarthritis in Rats
Osteoarthritis (OA) is a complex and increasingly prevalent condition affecting an estimated 600 million people worldwide, significantly diminishing quality of life. Understanding OA as both an inflammatory and neurological disease presents challenges for treatment, with no approved disease-modifyin...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-10-28 | PXD060558 | Pride
Pain Mi-rat Osteoarthritis Mass spectrometry Neuropeptide Peptidome 
UnknownAnnotation of novel neuropeptide precursors in the migratory locust based on transcript screening of a public EST database and mass spectrometry.
Not available
S-EPMC1574313 | biostudies-literature
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