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UnknownAutoimmune nodopathy with anti-NF186 antibodies following SARS-CoV-2 infection: a case report.
Not available
S-EPMC12486672 | biostudies-literature
UnknownParaneoplastic Syndrome Presenting Combined Central and Peripheral Demyelination Associated with Anti-CV2/CRMP5 and Anti-NF186 Antibodies: A Case Report.
Not available
S-EPMC10046875 | biostudies-literature
UnknownAtaxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186.
Not available
S-EPMC6769111 | biostudies-literature
UnknownCase Report: Anti-NF186+ CIDP After Receiving the Inactivated Vaccine for Coronavirus Disease (COVID-19).
Not available
S-EPMC8964034 | biostudies-literature
ProteomicsMapping Axon Initial Segment Structure and Function by Iterative Proximity Biotinylation
We constructed AIS-targeted biotin ligase by generating fusion proteins of BirA* with NF186, Ndel1, and Trim46; these chimeras mapped the molecular organization of intracellular membrane, cytosolic, and microtubule compartments of the AIS, respectively
ORGANISM(S): Rattus norvegicus (Rat) 
2020-01-13 | PXD016272 | Pride
Bioid Axon initial segments 
UnknownDirect fluorescent labeling of NF186 and NaV1.6 in living primary neurons using bioorthogonal click chemistry.
Not available
S-EPMC10323244 | biostudies-literature
TranscriptomicsLoss of Neurofascin 186 and Ankyrin G in Purkinje Cells Causes Disruption of Axon Initial Segments, Neurodegeneration and Cerebellar Ataxia
The axon initial segment (AIS) is essential for initiating action potentials and maintaining neuronal polarity, yet the developmental roles of its core molecular components—Neurofascin 186 (NF186) and Ankyrin G (AnkG)—remain incompletely defined in cerebellar Purkinje cells. Here, we generated Purki...
ORGANISM(S): Mus musculus 
2026-03-27 | GSE322737 | GEO
TranscriptomicsThe highly localized interaction between Neurofascin-186 and Gliomedin promotes subcellular innervation by the chandelier cell
A variety of cortical inhibitory interneuron (IN) subtypes differentially but coordinately operate in local circuits to process neuronal signals. The subcellular arrangement of IN synaptic outputs contributes to subtype-specific functional specialization. However, it remains poorly understood what i...
ORGANISM(S): Mus musculus 
2025-11-22 | GSE310319 | GEO
ProteomicsAnalysis of NF186 proximity proteomes across neuronal development using Nfasc antibodies in an antibody-directed proximity biotinylation strategy combined with mass spectrometry
Axon initial segment (AIS) cell surface proteins mediate key biological processes in neurons including action potential initiation and axo-axonic synapse formation. However, few AIS cell surface proteins have been identified. Here, we used antibody-directed proximity biotinylation to define the cell...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-05 | PXD043805 | Pride
Nf186 Bar Neuronal development Proximity labeling 
UnknownClinical profile of autoimmune nodopathy with anti-neurofascin 186 antibody.
Not available
S-EPMC10270277 | biostudies-literature
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