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Mitochondrial activity is critical for cellular vitality and organismal longevity, yet underlying regulatory mechanisms spanning these different levels of organization remain elusive. From RNAi screens for mitochondrial biogenesis, we discovered NFYB-1, a subunit of the NF-Y transcriptional complex,...
ORGANISM(S): Caenorhabditis elegans 
2020-03-11 | PXD013233 | Pride
NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin
Mitochondrial activity is critical for cellular vitality and organismal longevity, yet underlying regulatory mechanisms spanning these different levels of organization remain elusive. From RNAi screens for mitochondrial biogenesis, we discovered NFYB-1, a subunit of the NF-Y transcriptional complex,...
ORGANISM(S): Caenorhabditis elegans 
2020-03-11 | GSE127917 | GEO
This is the ChIP-seq control of transgenic worms expressing nfyb-1-eGFP fusion proteins. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Caenorhabditis elegans 
2024-02-27 | GSE256946 | GEO
ChIP-seq on transgenic worms expressing nfyb-1-eGFP fusion proteins. The IP was performed using an anti-GFP antibody. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14...
ORGANISM(S): Caenorhabditis elegans 
2024-02-27 | GSE258139 | GEO
It is known that CBFB-MYH11, the fusion gene generated by inversion of chromosome 16 in human acute myeloid leukemia, is causative for oncogenic transformation. However, the mechanism by which CBFB-MYH11 initiates leukemogenesis is not clear. Previously published reports showed that CBFB-MYH11 domin...
ORGANISM(S): Mus musculus 
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