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Glucocorticoids used in pharmacological doses for the treatment of a variety of medical conditions, and endogenous glucocorticoid excess – Cushing’s syndrome, may result in several adverse effects, but currently there is no clinically useful biomarker of glucocorticoid activity. A three-phase prote...
ORGANISM(S): Homo sapiens (Human) 
2021-03-14 | PXD019945 | Pride
Transcriptional profiles of snails sized 12-20mm exposed to E. paraensei and unexposed controls Keywords: Dose response Five individual snails from the treatment group were analyzed at 12hours, 1, 2, 4, 8, and 16 days. Five unexposed control snails were also analyzed.
ORGANISM(S): Biomphalaria glabrata 
Quantitative analysis of relative levels of RNA modifications in small (primarily tRNA) and large (primarily 16S/23S rRNA) RNAs isolated from Enterococcus faecalis OG1RF across a growth time course in BHI media.
2026-08-20 | MTBLS14602 | MetaboLights
BruUV-seq utilizes UV light to introduce transcription-blocking DNA lesions randomly in the genome prior to bromouridine-labeling and deep sequencing of nascent RNA. By inhibiting transcription elongation, but not initiation, pre-treatment with UV light leads to a redistribution of transcription rea...
ORGANISM(S): Homo sapiens 
Context Glucocorticoids used in pharmacological doses for the treatment of a variety of medical conditions, and endogenous glucocorticoid excess – Cushing’s syndrome, may result in several adverse effects, but currently there is no clinically useful biomarker of glucocorticoid activity. Objective T...
ORGANISM(S): Homo Sapiens 
2021-03-15 | PXD019972 | panorama

Consumption of sugar-rich diets adversely affects health and reduces life expectancy through the excessive production and storage of triacylglycerides (TAGs) leading to metabolic dysfunction. Here, using Drosophila melanogaster, we identify the conserved Ras/MAPK signalling pathway as a key media...

2026-09-02 | MTBLS14468 | MetaboLights
Transcriptional profiles ofBS-90 snails sized 8-12mm exposed to E. paraensei (BS-90 are susceptible) and S. mansoni (BS-90 are resistant) and unexposed controls Keywords: Dose response Five individual snails from the treatment group were pooled to make up 3 repliactes. After exposure to the indica...
ORGANISM(S): Biomphalaria glabrata 
Cytokines are commonly measured by immunoassays, which have limited multiplexing capacity, are costly and can exhibit cross-reactivity. Although multiple reaction monitoring (MRM) mass spectrometry is a cost-effective method for multiplex measurement of peptides, the ability to detect the relatively...
ORGANISM(S): Homo sapiens (Human) 
2020-02-19 | PXD015407 | Pride
Development of a clinically relevant animal models of RCC for preclinical investigations. For DNA copy number analysis, the Sty I (250K) SNP array of the 500K Human Mapping Array (Affymetrix) was used. Arrays were scanned by GeneChip Scanner 3000 7G. Probe-level signal intensities were normalized to...
ORGANISM(S): Homo sapiens 
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