Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of brains from wild type and beta4 nicotinic acetylcholine receptor (nAChR) subunit deficient mice to identify genes that might be related to beta4-containing nAChRs activity
Studies using mice with beta4 nicotinic acetylcholine receptor (nAChR) subunit deficiency (beta4-/- mice) helped reveal the roles of this subunit in bradycardiac response to vagal stimulation, nicotine-induced seizure activity and anxiety. In order to identify genes that might be related to beta4-co...
ORGANISM(S): Mus musculus 
2007-11-27 | E-GEOD-5320 | biostudies-arrayexpress
Proteomicsα7 Nicotinic Acetylcholine Receptor-Associated Signaling in U87MG Glioblastoma Cells (LFQ, Orbitrap Elite)
This project investigates the role of α7 nicotinic acetylcholine receptor (α7 nAChR) signaling in glioblastoma using the U87MG human glioblastoma cell line. Cells were treated with selective α7 nAChR ligands (10 μM of agonist PNU282987, 1 μM of positive allosteric modulator PNU120596, 1 μM of antago...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD070911 | Pride
Glioblastoma  u87mg  α7 nicotinic acetylcholine receptor  choline  total proteome  label-free quantification  orbitrap elite  proteomics 
Genomicsα7 Nicotinic Acetylcholine Receptor Regulates Macrophage-Mediated Neuroinflammation in Dry Eye Disease
α7 Nicotinic Acetylcholine Receptor Regulates Macrophage-Mediated Neuroinflammation in Dry Eye Disease
PRJNA1095925 | ENA
GenomicsShort-term depletion of nicotinic acetylcholine receptor subunits in Drosophila enterocytes
Short-term depletion of nicotinic acetylcholine receptor subunits in Drosophila enterocytes
PRJNA988543 | ENA
GenomicsRNA sequencing data describing transcriptional changes in aorta of ApoE-/- mice after alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation.
RNA sequencing data describing transcriptional changes in aorta of ApoE-/- mice after alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation.
PRJNA542796 | ENA
TranscriptomicsTranscription profiling of rat heart tissue from animals aged 4 and 22 months
Myocardial aging leads to a reduction of beta-adrenergic receptor-induced metabolic and contractile responsiveness. We hypothesize that a change in the patterns of gene expression is important in these age-related events. To test this, hearts were harvested from young and aged male rats (3-4 and 20-...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-421 | biostudies-arrayexpress
GenomicsAlpha7 Nicotinic Acetylcholine Receptor Mediates Chronic Nicotine Inhalation-Induced Cardiopulmonary Dysfunction
Alpha7 Nicotinic Acetylcholine Receptor Mediates Chronic Nicotine Inhalation-Induced Cardiopulmonary Dysfunction
PRJNA803731 | ENA
Transcriptomicswhole brains from nicotinic acetylcholine receptor subunit mutant mice and littermate controls
Studies using mice with beta4 nicotinic acetylcholine receptor (nAChR) subunit deficiency (beta4-/- mice) helped reveal the roles of this subunit in bradycardiac response to vagal stimulation, nicotine-induced seizure activity and anxiety. In order to identify genes that might be related to beta4-co...
ORGANISM(S): Mus musculus 
2006-09-22 | GSE5320 | GEO
ProteomicsDrosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins
Description Drosophila melanogaster nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that present a target for insecticides. However, a better understanding of in vioreceptor subunit composition is needed for effective design of insecticides. Alpha-neurotxins are known as pe...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-10-11 | PXD028484 | Pride
Nachrs Pull-down Toxins Smalps 
TranscriptomicsShort-term depletion of nicotinic acetylcholine receptor subunits in Drosophila enterocytes
Bulk RNAseq from whole Drosophila melanogaster guts expressing either mCherry-RNAi (control) or RNAi against nicotinic acetylcholine receptor subunits β1 and β3 (nAchRβ1 and nAchRβ3) under control of a enterocyte-specific driver to assess their role in barrier function.
ORGANISM(S): Drosophila melanogaster 
2023-08-23 | GSE236069 | GEO
Sort   by:  
 Page size