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ProteomicsIdentification of penaeid shrimp hemocyanin acetylation sites
To identify the acetylation site(s) on hemocyanin (PvHMC) that modulate its functions, purified PvHMC from the plasma of HDACs inhibitor (NAM and TSA) treated shrimp was analyzed by tandem mass spectrometry. Four lysine acetylation sites (K179, K188, K648, and K653) were found on the small molecular...
ORGANISM(S): Penaeus vannamei 
2022-07-19 | PXD030949 | Pride
Hemocyanin Penaeus vannamei Acetylation sites 
ProteomicsComprehensive analysis of the host-virus interactome of SARS-CoV-2
Host-virus protein-protein interaction is the key component of SARS-CoV-2 life cycle, which can be targeted for therapeutic intervention. Thus, we conducted a comprehensive interactome study between the virus and host cell using tandem affinity purification (TAP) and BioID2 labeling strategies. In a...
ORGANISM(S): Homo sapiens (Human) 
2021-06-29 | PXD023209 | Pride
Sfb-tap Sars-cov-2 Human coronavirus Host-virus protein-protein interaction Bioid2 Interactome 
ProteomicsInteractome of AMPK complex study using TAP-MS
The adenosine monophosphate-activated protein kinase (AMPK) complex is a key enzyme in regulating cellular energy homeostasis. This complex is well studied and it is known to function in many cellular pathways. However, the interactome of AMPK complex has not yet been systematically established, alt...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD015466 | Pride
Interactome Ampk Tap 
ProteomicsInteractome of ferroptosis pathways genes
We conducted a proteomic interactome analysis of well-known regulators of ferroptosis, ACSL4, LPCAT3, ALOX12, ALOX15, PEBP1, NCOA4, GCH1, FSP1, DHODH, SLC7A11, GCLC, GCLM, GSS, and GPX4. Take LPCAT3 as an example, we uncovered an opposing role of its binding protein CEPT1 in suppressing ferroptosis.
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD035146 | Pride
Ferroptosis Tap-ms Interactome 
ProteomicsRaw data of 218 FFPE tissue proteomes containing 144 tissue samples from seven organs of fatal VID-19 cases and 74 control specimens from 56 non-COVID-19 individuals
144 tissue samples from postmortem lung, liver, kidney, heart, spleen, testis and thyroid collected from 19 COVID-19 cases and 74 control specimens from 56 non-COVID-19 individuals were analyzed by PCT and TMT 16-plex based proteomics.
ORGANISM(S): Homo Sapiens 
2020-12-11 | PXD022775 |
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