OBJECTIVE: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare acquired immune-mediated neuropathy. Although microbial infection is potentially a contributing factor, a causative link between CIDP and microbial infection remains unclear. There is also no de...
Heterosis, or hybrid vigor, refers to the phenomenon where F1 hybrids outperform their parental inbred lines. Despite more than a century of intensive research across various species, the genetic basis and environmental regulation of heterosis, particularly belowground, remain poorly understood. ...
Untargeted fecal metabolomics using UHPLC-MS/MS to analyze microbiota-dependent metabolic changes in C57BL/6 mice exposed to 6PPD-quinone (6PPD-Q) with/without antibiotic-mediated gut microbiota depletion. Key pathways include tryptophan and nicotinamide metabolism linked to intestinal barrier fu...
Background: After spinal cord injury (SCI), lipid metabolism dysregulation at the lesion site exacerbates secondary damage. The transcription factor pu.1 has been implicated as a negative regulator of multiple lipid metabolism-related genes and pathways. However, its role in post-SCI lipid metabo...