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ProteomicsMouse epididymis LC-MSMS - Male Fertility Potential Molecular Mechanisms Revealed by iTRAQ-Based Quantitative Proteomic Analysis of the Epididymis from Wip1-/- Mice
The wild-type p53-induced phosphatase 1 (WIP1) frustrated mice exhibited defects in reproductive organs. This study aimed to understand how Wip1 deficiency affects the spermatogenesis or maturation. We employed the Wip1-/- mouse model and conducted a gel-free iTRAQ LC-MS/MS based quantitative proteo...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-16 | PXD010125 | Pride
Lc-msms Mouse Sperm Itraq Epididymis 
ProteomicsIntegrative proteomic and phosphoproteomic profiling of testis from Wip1-knockout mice: insights into mechanisms of reduced fertility
Spermatogenesis plays an important role in the mammalian testis, involving in the complex processes of mitosis, meiosis, and spermiogenesis. Spermatogenesis may also be disrupted in the absence of the immunological and ‘fence’ functions of the BTB, resulting in male subfertility or infertility. Mice...
ORGANISM(S): Mus musculus (Mouse) 
2018-11-02 | PXD009220 | Pride
Fertility Proteomic Phosphoproteomic Knockout mice Testis Wip1 
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