Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse hippocampal slices after NMDA or forskolin-rolipram-0 Mg2+ or bicuculline treatment
Effect of different chemical stimuli (NMDA(N-methyl-D-aspartic acid), forskolin/rolipram/0 Mg, bicuculline) on gene expression after 1 h of stimulation in hippocampal slices
ORGANISM(S): Mus musculus 
2008-06-01 | E-MEXP-1184 | biostudies-arrayexpress
TranscriptomicsGlobal gene profiling comparison between hydrogen sulfide- and N-methyl-D-aspartate-induced neuronal deaths
Hydrogen sulfide (H2S), present in abundance in the mammalian brain, has recently been demonstrated to induce a dose- and time-dependent apoptotic-necrotic continuum in murine primary cortical neurons, which was successfully attenuated upon application of N-methyl-D-aspartate (NMDA) receptor antagon...
ORGANISM(S): Mus musculus 
2013-01-23 | E-GEOD-16035 | biostudies-arrayexpress
GenomicsGLP-1 directed NMDA receptor antagonism for obesity treatment [II]
GLP-1 directed NMDA receptor antagonism for obesity treatment [II]
PRJNA1029627 | ENA
GenomicsGLP-1 directed NMDA receptor antagonism for obesity treatment [I]
GLP-1 directed NMDA receptor antagonism for obesity treatment [I]
PRJNA1023883 | ENA
TranscriptomicsStudy the effect of mesenchymal stem cells on isolated cortical neurons before and after NMDA treatment
Primary cortical neurons were isolated from E15 mice and after 5 days in vitro were untreated or treated for 24 h with mesenchymal stem cell conditioned medium and then untreated or treated for a further 24 h with NMDA. Neuron gene expression was profiled and compared between the four different cond...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-26279 | biostudies-arrayexpress
GenomicsNMDA receptor positive allosteric modulator induced genome wide gene expression changes in neuronal cultures
NMDA receptor positive allosteric modulator induced genome wide gene expression changes in neuronal cultures
PRJNA578282 | ENA
ProteomicsEnhanced hippocampal LTP but typical NMDA receptor and AMPA receptor function in a novel rat model of CDKL5 deficiency disorder
Background: Mutations in the X-linked gene cyclin-dependent kinase-like 5 (CDKL5) cause a severe neurological disorder characterised by early-onset epileptic seizures, autism and intellectual disability (ID). Impaired hippocampal function has been implicated in other models of monogenic forms of aut...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-08-14 | PXD043246 | Pride
Hippocampus Rat Cdk Nmda Brain 
ProteomicsGLP-1 directed NMDA receptor antagonism for obesity treatment
The N-methyl-D-aspartate (NMDA) receptor is a glutamate-activated cation channel critical to many processes in the brain. Genome-wide association studies (GWAS) suggest that glutamatergic neurotransmission and NMDA receptor-mediated synaptic plasticity is important for body weight homeostasis1. Here...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-26 | PXD045816 | Pride
Hypothalamus Glp-1 Obesity 
TranscriptomicsRegulation of neuronal gene expression and survival by basal NMDA receptor activity: a role for Histone Deacetylase 4
Gene expression analysisis of NR2A and NR2B containing NMDA receptors after treatment with AP5, NVP-AAM077 and Ro25-6981 4 conditions, vehicle, AP5, Ro25, and NVP, 4-5 replicates of each sample
ORGANISM(S): Mus musculus 
2014-10-23 | E-GEOD-54708 | biostudies-arrayexpress
TranscriptomicsGLP-1 directed NMDA receptor antagonism for obesity treatment [I]
The N-methyl-d-aspartate (NMDA) receptor is a glutamate-activated cation channel critical to many processes in the brain. Genome-wide association studies (GWAS) suggest that glutamatergic neurotransmission and NMDA receptor-mediated synaptic plasticity is important for body weight homeostasis1. Here...
ORGANISM(S): Mus musculus 
2024-05-14 | GSE244607 | GEO
Sort   by:  
 Page size