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TranscriptomicsRNA-seq of estrogen (E2) induced changes of mRNA expression in Sus scrofa male and female blastocysts derived from embryonic day 10
Environmental estrogens may affect epigenetic programming as early as the period of preimplantation development. Therefore, we analyzed the effects of continuous gestational estradiol-17β (E2) exposure on male and female embryos. A low dose, close to the no-observed effect level (NOEL - 10 µg E2/kg ...
ORGANISM(S): Sus scrofa 
2018-10-16 | E-MTAB-6263 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of chicken wild type and tumor supressor 53Bp1 knockout lymphoblast cells
Effect of abrogation of the tumour supressor 53Bp1 on gene expression in the chicken DT40 model system
ORGANISM(S): Gallus gallus 
2011-05-07 | E-MEXP-2721 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MSC isolated from human bone marrow aspirates differentiated to chondrocytes with BMP2 or TGFbeta-3, vs undifferentiated MSC sampled at multiple time points
Human mesenchymal stem cells (MSC) display a high potential for the development of novel treatment strategies for cartilage repair. However, the pathways involved in their differentiation to functional and non hypertrophic chondrocytes remain largely unknown, despite the work on embryologic developm...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10315 | biostudies-arrayexpress
UnknownGenetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Not available
S-EPMC3431328 | biostudies-literature
UnknownCirculating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program.
Not available
S-EPMC4158711 | biostudies-literature
UnknownCommon variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.
Not available
S-EPMC4154629 | biostudies-literature
UnknownEffects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Not available
S-EPMC3439414 | biostudies-literature
UnknownTCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program.
Not available
S-EPMC3144193 | biostudies-literature
UnknownThe Impact of Physical Activity on the Prevention of Type 2 Diabetes: Evidence and Lessons Learned From the Diabetes Prevention Program, a Long-Standing Clinical Trial Incorporating Subjective and Objective Activity Measures.
Not available
S-EPMC7783946 | biostudies-literature
TranscriptomicsSmall RNA-seq analysis of single porcine blastocysts revealed that maternal estradiol-17beta exposure does not affect miRNA isoform (isomiR) expression
Small RNA sequencing of 36 porcine embryo samples collected on Day 10 of pregnancy detected miRNA sequences mapping to known and predicted porcine miRNAs, and novel miRNAs highly conserved in human and cattle. A set of highly abundant miRNAs was identified as well as a large number of rarely express...
ORGANISM(S): Sus scrofa 
2018-07-23 | E-MTAB-6201 | biostudies-arrayexpress
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