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TranscriptomicsComparison of adult intact naive C57Bl/6 Nogo-A KO versus WT spinal cord
Nogo-A localized on myelin adaxonal membrane in the adult CNS is well known for its role as neurite outgrowth inhibitor following a lesion. Nogo-A KO mice show enhanced regenerative/compensatory fiber growth following CNS lesion. However, changes undergoing in their intact CNS have not been studied....
ORGANISM(S): Mus musculus 
2010-11-01 | E-GEOD-11276 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat intact CNS tissue in vitro using rat organotypic hippocampal slice cultures after anti-Nogo-A antibody treatment
The neurite outgrowth inhibitory myelin protein Nogo-A has been well studied in the context of central nervous system (CNS) injury and disease. We studied the effects of the application of neutralizing anti-Nogo-A antibodies (11C7 and 7B12) in intact CNS tissue in vitro using rat organotypic hippoca...
ORGANISM(S): Rattus norvegicus 
2008-11-15 | E-GEOD-12483 | biostudies-arrayexpress
GenomicsNogo maintains muscle integrity and regulates muscle regeneration via modulating Nogo-A expression
Nogo maintains muscle integrity and regulates muscle regeneration via modulating Nogo-A expression
PRJNA545456 | ENA
GenomicsEffects of Nogo-A deletion on the trigeminal ganglion
Effects of Nogo-A deletion on the trigeminal ganglion
PRJNA1193571 | ENA
ProteomicsNogo-A modulates gene expression to fine-tune enamel development
Nogo-A is a major player in neural development and regeneration, and it is the target of several clinical trials. However, its functions outside the nervous system are mostly unknown. We observed that Nogo-A is expressed in dental epithelial cells, responsible for the formation of enamel, and we sho...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-20 | PXD030386 | Pride
Differentiation Amelogenesis Lc-ms Tooth Interactome Nogo-a Development Enamel Transcriptome Dda 
TranscriptomicsNogo maintains muscle integrity and regulates muscle regeneration via modulating Nogo-A expression
Nogo, also called RTN4, functions through three isoforms including Nogo-A, -B, and -C. Although Nogo-A is a well-known CNS inhibitor and the level of Nogo-A is increased in muscles of ALS patients, its role in the regulation of skeletal muscle homeostasis and regeneration is still vague. In this stu...
ORGANISM(S): Mus musculus 
2019-05-31 | GSE131955 | GEO
GenomicsEffects of Nogo-A deletion in the dental epithelium of the continuously growing mouse incisor
Effects of Nogo-A deletion in the dental epithelium of the continuously growing mouse incisor
PRJNA674603 | ENA
TranscriptomicsEffects of Nogo-A deletion on the trigeminal ganglion
Nogo-A is a major regulator of neural development and regeneration in the central nervous system, but its role in tooth innervation remains largely unknown. Neurons of the trigeminal ganglion innervate the teeth. We showed that Nogo-A is expressed in the trigeminal ganglion and tooth-related nerve f...
ORGANISM(S): Mus musculus 
2024-12-04 | GSE283391 | GEO
TranscriptomicsAnti-Nogo-A antibody treatment of Rat Hippocampal Slice Cultures
The neurite outgrowth inhibitory myelin protein Nogo-A has been well studied in the context of central nervous system (CNS) injury and disease. We studied the effects of the application of neutralizing anti-Nogo-A antibodies (11C7 and 7B12) in intact CNS tissue in vitro using rat organotypic hippoca...
ORGANISM(S): Rattus norvegicus 
2008-11-12 | GSE12483 | GEO
TranscriptomicsComparison of adult intact naive C57Bl/6 Nogo-A KO versus WT spinal cord
Nogo-A localized on myelin adaxonal membrane in the adult CNS is well known for its role as neurite outgrowth inhibitor following a lesion. Nogo-A KO mice show enhanced regenerative/compensatory fiber growth following CNS lesion. However, changes undergoing in their intact CNS have not been studied....
ORGANISM(S): Mus musculus 
2010-11-01 | GSE11276 | GEO
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