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TranscriptomicsRNA-seq of NOMO-1 cell line
RNA-seq of NOMO-1 cell line
ORGANISM(S): Homo sapiens 
2019-08-30 | E-MTAB-8010 | biostudies-arrayexpress
TranscriptomicsEffect of ZFX shRNA mediated knockdown in the human AML cell line NOMO-1
Acute myeloid leukemia (AML) and acute T-lymphoblastic leukemia (T-ALL) maintain the undifferentiated phenotype and proliferative capacity of their respective cells of origin, hematopoietic stem/progenitor cells and immature thymocytes. The mechanisms that maintain these progenitor-like characterist...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-43021 | biostudies-arrayexpress
GenomicsRNA-seq of NOMO-1 cell line
RNA-seq of NOMO-1 cell line
PRJEB32843 | ENA
ProteomicsStructural surfaceomics of Nomo-1 using PhoX cross-linker with timsTOF
The project aimed to profile the cell surface proteins of Nomo-1 (AML cell line) using structural surfaceomics for identification of protein conformation-based cancer antigens thereby expanding the toolkit for cancer target discovery for immunotherapeutic targeting. To achieve the goal, cell surface...
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD035591 | Pride
Xl-ms Phox Cell surfaceome Nomo-1 Aml 
GenomicsTranscriptome analysis of NOMO-1 cells with MSLN knockout
Transcriptome analysis of NOMO-1 cells with MSLN knockout
PRJNA1310324 | ENA
ProteomicsGeneration of Nomo-1 cell surfaceome database
The goal was to build a custom proteome database for cell surface proteins of Nomo-1 (AML cell line). Such custom database was meant to facilitate cross-linking (XL-MS) of cell surface proteins for this cell line using non-cleavable cross-linkers. Using such custom database helps with the computatio...
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD035404 | Pride
Aml and cell surfaceome Nomo-1 
ProteomicsStructural surfaceomics of Nomo-1 using DSSO cross-linker with MS3 approach
The project aimed to profile the cell surface proteins of Nomo-1 (AML cell line) using structural surfaceomics for identification of protein conformation-based cancer antigens thereby expanding the toolkit for cancer target discovery for immunotherapeutic targeting. To achieve the goal, cell surface...
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD035589 | Pride
Ms3 Dsso Xl-ms Cell surfaceome Nomo-1 Aml 
TranscriptomicsTranscriptome analysis of NOMO-1 cells with MSLN knockout
MSLN is a newly identified AML target. Because MSLN is not expressed in normal bone marrow specimens, it is an attractive immunotherapy target. However, the function of MSLN in AML is unknown. We generated NOMO-1 cells with CRISPR/CAS9 knockout and performed transcriptome analysis to understand the ...
ORGANISM(S): Homo sapiens 
2026-05-15 | GSE306271 | GEO
GenomicsRNA-seq in wild-type, METTL16-knockout, and METTL16 rescue NOMO-1 cells
RNA-seq in wild-type, METTL16-knockout, and METTL16 rescue NOMO-1 cells
PRJNA785629 | ENA
TranscriptomicsThe apoptotic network and expression of BH3-containing proteins predict phenotypic response to BET bromodomain inhibitors
Small molecule inhibitors of the bromodomain and extraterminal (BET) family of proteins are in clinical trials for a variety of cancers, but patient selection strategies are limited. This is due in part to the heterogeneity of response following BET inhibition (BETi), which includes differentiation...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-69383 | biostudies-arrayexpress
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