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MetabolomicsNMR-Based Metabolomics of Non-Human Primate Ocular Tissues: A Dataset
Model animals are employed in experiments as substitutes for human tissues and fluids, particularly when accessing particular human samples (such as cerebrospinal fluid, brain, ocular tissues, etc.) poses significant challenges or is ethically constrained. Nonhuman primates are frequently regarded a...
2023-11-16 | MTBLS8943 | MetaboLights
MetabolomicsHigh Resolution GC-MS Metabolomics of Non-Human Primate Serum
Not available
ORGANISM(S): Papio hamadryas 
ST000972 | MetabolomicsWorkbench
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
TranscriptomicsPedigreed Primate Embryonic Stem Cells Express Homogeneous Familial Gene Profiles
Pedigreed primate ESCs display homogeneous and reliable expression profiles. These similarities to mouse ESCs suggest that heterogeneities found among hESCs result from their disparate origins rather than intrinsic biological limitations with primate embryonic stem cells. Keywords: different nhpESC ...
ORGANISM(S): Macaca mulatta 
2008-04-14 | E-GEOD-7534 | biostudies-arrayexpress
TranscriptomicsPrimate iPS cells as tools for evolutionary analyses
Induced pluripotent stem cells (iPSCs) are regarded as a central tool to understand human biology in health and disease. Similarly, iPSCs from closely related species should be a central tool to understand human evolution and to identify conserved and variable patterns of iPSC disease models. Here, ...
ORGANISM(S): Macaca fascicularis 
2014-02-19 | E-GEOD-50781 | biostudies-arrayexpress
TranscriptomicsGene expression changes during primate postnatal brain development
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain...
ORGANISM(S): Macaca mulatta 
2009-03-09 | E-GEOD-11512 | biostudies-arrayexpress
TranscriptomicsPapio anubis Transcriptome or Gene expression
This data set consists of tissue-specific RNA-seq reads from 14 different tissues from a single female adult olive baboon (Papio anubis): bone marrow, brain cerebellum, brain frontal cortex, brain pituitary, brain temporal lobe, colon, heart, kidney, liver, lymph node, spleen, lung, skeletal muscle ...
ORGANISM(S): Papio anubis 
2013-12-09 | E-MTAB-2848 | biostudies-arrayexpress
TranscriptomicsComparative genomic analysis of human and non-human primate CD34+ MPBSCs exposed to PGE2
Abstract: Hematopoietic stem cells (HSCs) are used in transplantation therapy to reconstitute the hematopoietic system. Human cord blood (hCB) transplantation has emerged as an attractive alternative treatment option when traditional HSC sources are unavailable, however, the absolute number of hCB H...
ORGANISM(S): Macaca mulatta 
2012-06-24 | E-GEOD-27126 | biostudies-arrayexpress
TranscriptomicsIdentification and characterization of two novel primate-specific histone H3 variants H3.X and H3.Y
Nucleosomal incorporation of specialized histone variants is an important mechanism to generate different functional chromatin states. Here we report the identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. Their mRNAs are found in certain human cell ...
ORGANISM(S): Homo sapiens 
2010-09-17 | E-GEOD-22415 | biostudies-arrayexpress
TranscriptomicsRegulatory element copy number differences shape primate expression profiles.
Gene expression differences are shaped by selective pressures and contribute to phenotypic differences between species. We identified 964 copy number differences (CNDs) of conserved sequences across 3 primate species and examined their potential effects on gene expression profiles. Samples with copy...
ORGANISM(S): Pan troglodytes 
2012-08-02 | E-GEOD-38572 | biostudies-arrayexpress
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