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ProteomicsImmune Complex-Induced Migration of Slan+ Non-Classical Monocytes
Slan+ Non-Classical Monocytes migrate on immobilized immune complexes. This phenomenon can be blcoked with anti-CD16 blocking antibodies and is therefore thought to be mediated via CD16 (FcyRIII). Nonetheless, other CD16+ cells, such as NK cells or neutrophils, as well as lineage related cells suchs...
ORGANISM(S): Homo sapiens (Human) 
2026-07-09 | PXD079927 | Pride
Slanmo Cd16a Immune complexes Fcyriiia Migration Slan+ non-classical monocytes Haptokinesis 
ProteomicsComprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes
Monocytes are a critical component of the cellular innate immune system, and can be subdivided into classical, intermediate and non-classical subsets on the basis of surface CD14 and CD16 expression. Classical monocytes play the canonical role of phagocytosis, and account for the majority of circula...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD013832 | Pride
Classical monocyte Monocyte Blood cell Cell surface Quantitative proteomics Tandem mass tag Plasma membrane 
ProteomicsTranscriptomic and proteomic profiling of non-classical monocytes unravels distinct pathogenic features in SLE
Current non-specific immunosuppressive treatments for Systemic Lupus Erythematosus (SLE) show modest efficacy. In SLE the monocytic/macrophage (Mo/Mφ) system plays a key role in the initiation and perpetuation of the systemic autoimmune response. However, the distinct functions of the Mo/Mφ cellular...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD042539 | Pride
Proteomics Non-classical monocytes Differentiation Cytokines M1 macrophages Autoimmunity Cell cycle Transcriptomics Systemic lupus erythematosus 
GenomicsTranscriptomic analysis of SLAN+ vs SLAN- non-classical monocytes
Transcriptomic analysis of SLAN+ vs SLAN- non-classical monocytes
PRJNA503867 | ENA
GenomicsAnalysis of human classical and non-classical monocytes compared to their dendritic cell counterpart.
Analysis of human classical and non-classical monocytes compared to their dendritic cell counterpart.
PRJNA418159 | ENA
GenomicsDonor non-classical monocytes recruit recipient classical monocytes from the spleen by activating donor alveolar macrophages
Donor non-classical monocytes recruit recipient classical monocytes from the spleen by activating donor alveolar macrophages
PRJNA701602 | ENA
GenomicsThe slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [scRNA-seq]
The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [scRNA-seq]
PRJNA1007605 | ENA
GenomicsGM-CSF Production by Non-Classical Monocytes Controls Antagonistic LPS-driven Functions In Allergic Inflammation
GM-CSF Production by Non-Classical Monocytes Controls Antagonistic LPS-driven Functions In Allergic Inflammation
PRJNA773923 | ENA
GenomicsRole of NR4A1 and non-classical monocytes in a mouse model of neovascular age-related macular degeneration
Role of NR4A1 and non-classical monocytes in a mouse model of neovascular age-related macular degeneration
PRJNA1001664 | ENA
GenomicsThe slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [Bulk RNA-seq]
The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [Bulk RNA-seq]
PRJNA1013061 | ENA
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