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The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. Here, we describe the the generation and multimodal LC-MS/MS analysis of >300,000 synthetic non-tryptic peptides labeled with tandem mass tags (TMT6plex).
ORGANISM(S): Homo sapiens (Human) 
2021-04-26 | PXD023120 | Pride
The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. Here, we describe the the generation and multimodal LC-MS/MS analysis of >300,000 synthetic non-tryptic peptides labeled with tandem mass tags (TMT6plex).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-10-09 | MSV000099441 | MassIVE
The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. Here, we describe the third iteration of the generation and multimodal LC-MS/MS analysis of >305,000 synthetic non-tryptic peptides representing HLA Class ...
ORGANISM(S): Homo sapiens (Human) 
2021-04-26 | PXD021013 | Pride
The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. Here, we describe the third iteration of the generation and multimodal LC-MS/MS analysis of >305,000 synthetic non-tryptic peptides representing HLA Class ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-21 | MSV000096140 | MassIVE
Identification of targets of the protein disulfide reductase thioredoxin using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) and thiol specific differential labeling with isotope-coded affinity tags (ICAT). Reduction of specific target disulfides is quantified by measuring rat...
ORGANISM(S): Hordeum vulgare 
2008-11-20 | GSE11650 | GEO
HeLa cells transfected with non-targeting control- and anti-SIK2 siRNA were left uninfected or infected with Salmonella and lysed 30 min pi. Following tryptic-digest peptides were labeled using TMT-pro 16-plex and phosphopeptides enriched. The endogenously tagged SIK2-HA IP workflow. Hela wild type ...
ORGANISM(S): Homo sapiens (Human) 
2021-05-06 | PXD021859 | Pride
Immunopeptidomics plays a crucial role in identifying targets for immunotherapy and vaccine development. Because the generation of immunopeptides from their parent proteins does not adhere to clear-cut rules, rather than being able to use known digestion patterns, every possible protein subsequence ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-17 | MSV000092456 | MassIVE
The aim of our study was to investigate cerebrospinal fluid (CSF) tryptic peptide profiles as potential diagnostic biomarkers for the discrimination of parkinsonian disorders. CSF samples were collected from individuals with parkinsonism, who had an uncertain diagnosis at the time of inclusion and w...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028842 | Pride
The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. Here, we describe the the generation and multimodal LC-MS/MS analysis of >500,000 tryptic synthetic peptides labeled with tandem mass tags (TMT6plex).
ORGANISM(S): Homo sapiens (Human) 
2021-01-11 | PXD023119 | Pride
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