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ProteomicsComparative Interactome Profiling of Nonstructural Protein 3 Across SARS-CoV-2 Variants Emerged During the COVID-19 Pandemic
SARS-CoV-2 virus and its variants have proven to be a threat to global health, in part due to their capacity for rapid evolution. SARS-CoV-2 variants that emerged throughout the COVID-19 pandemic exhibited variations in virulence, leading to diminished vaccine protection and modulating disease sever...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD061195 | Pride
Virus-host interactions Affinity purification-mass spectrometry Variants Nsp3 
ProteomicsComparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs
Human coronaviruses have become an increasing threat to global health; three highly pathogenic strains have emerged since the early 2000s, including most recently SARS-CoV-2, the cause of COVID-19. A better understanding of the molecular mechanisms of coronavirus pathogenesis is needed, including ho...
ORGANISM(S): Homo sapiens (Human) 
2021-07-01 | PXD024566 | Pride
Ap-ms Sars-cov-2 Covid-19 
UnknownInterferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3.
Not available
S-EPMC6126873 | biostudies-literature
UnknownUnmasking the active helicase conformation of nonstructural protein 3 from hepatitis C virus.
Not available
S-EPMC3126282 | biostudies-literature
ProteomicsProximity-dependent biotinylation detects association between stress granule associated proteins and SARS coronavirus nonstructural protein 1
Severe acute respiratory syndrome coronavirus (SARS-CoV and SARS-CoV-2) nonstructural protein 1 (nsp1) is a critical viral protein that suppresses host gene expression by blocking the assembly of the ribosome on host messenger RNAs (mRNA). Using proximity-dependent biotinylation assay followed by pr...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025980 | Pride
Nsp1 Stress granule Sars-cov Sars-cov-2 Bioid2 
UnknownN terminus of SARS-CoV-2 nonstructural protein 3 interrupts RNA-driven phase separation of N protein by displacing RNA.
Not available
S-EPMC11538861 | biostudies-literature
ProteomicsRSV nonstructural protein 1 (NS1) HDX LC-MS data
Raw liquid chromatography-mass spectrometry (LC-MS) datafiles acquired for hydrogen-deuterium exchange (HDX) of RSV nonstructural protein 1 (NS1)
ORGANISM(S): Human Respiratory syncytial virus 9320 
2025-05-07 | PXD054005 | Pride
Rsv ns1 hdx-ms 
UnknownProteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3.
Not available
S-EPMC2395186 | biostudies-literature
UnknownDifferences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest Virus.
Not available
S-EPMC4621116 | biostudies-literature
UnknownPestivirus virion morphogenesis in the absence of uncleaved nonstructural protein 2-3.
Not available
S-EPMC3255886 | biostudies-literature
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