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ProteomicsDrug sensitivity, gene dependency and proteogenomic correlates of the spectrum of telomere maintenance mechanisms in cancer cells
Replicative immortality is a hallmark of cancer, driven by activation of telomere maintenance mechanisms (TMM), that is yet to be therapeutically exploited. To expedite discoveries that will enable development of TMM-targeted therapeutics, we have generated a resource of telomere biology metrics for...
ORGANISM(S): Homo sapiens (Human) 
2025-10-17 | PXD058664 | Pride
Tmm Cancer Proteomics Swath-dia Telomere biology 
ProteomicsProteomic-based computational stratification of intermediate-risk prostate cancer patients.
Gleason grading is an important prognostic indicator for prostate adenocarcinoma and is crucial for patient treatment decisions. However, intermediate-risk patients diagnosed in Gleason Grade Groups (GG) 2 and GG3 can harbour either aggressive or non-aggressive disease, resulting in under- or over-t...
ORGANISM(S): Homo sapiens (Human) 
2023-11-30 | PXD041005 | Pride
Survival analysis Mass spectrometry Swath-ms Data analysis Prostate adenocarcinoma Gleason grading 
ProteomicsFederated deep learning enables cancer subtyping by proteomics
Artificial intelligence (AI) applications in biomedical settings face challenges such as data privacy and regulatory compliance. Federated Deep Learning (FDL) effectively addresses these issues. We developed ProCanFDL, where local models were trained on simulated sites using proteomic data drawn fro...
ORGANISM(S): Homo sapiens (Human) 
2025-05-29 | PXD056810 | Pride
Procanfdl Pan-cancer Human Swath-ms Proteomics Federated deep learning 
ProteomicsRecombinant SWATH library for identification of low abundant human plasma proteins
Recombinant SWATH library for identification of low abundant human plasma proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-04 | MSV000086411 | MassIVE
UnknownSelf-reported symptom study of COVID-19 chemosensory dysfunction in Malaysia.
Not available
S-EPMC8826975 | biostudies-literature
UnknownHigher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC11872607 | biostudies-literature
UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
UnknownBaricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
Not available
S-EPMC9333998 | biostudies-literature
UnknownHigher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10156147 | biostudies-literature
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