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GenomicsCaproicibacterium sp. NSD3
Caproicibacterium sp. NSD3 Genome sequencing
PRJNA1308095 | ENA
GenomicsCaproicibacterium sp. NSD3
Caproicibacterium sp. NSD3 Genome sequencing
PRJNA1347543 | ENA
ProteomicsAn NSD3-targeting PROTAC suppresses the NSD3 and cMyc oncogenic nodes in cancer cells
Nuclear receptor binding SET domain protein 3 (NSD3), a gene located within the 8p11-p12 amplicon frequently detected in cancers, encodes a chromatin modulator and an attractive onco-target. However, agent that can effectively suppress the NSD3-mediated oncogenic actions is currently lacking. We rep...
ORGANISM(S): Homo sapiens (Human) 
2021-08-27 | PXD021901 | Pride
Histone Chromatin Nsd3 Epigenetics Cmyc Protac Degrader 
GenomicsAn NSD3-targeting PROTAC (Proteolysis Targeting Chimeric) suppresses the NSD3 and cMyc oncogenic nodes in cancer cells
An NSD3-targeting PROTAC (Proteolysis Targeting Chimeric) suppresses the NSD3 and cMyc oncogenic nodes in cancer cells
PRJNA664766 | ENA
GenomicsNSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler (ChIP-Seq)
The bromodomain and extraterminal (BET) protein BRD4 is a therapeutic target in acute myeloid leukemia (AML). Here, we demonstrate that the AML maintenance function of BRD4 requires its interaction with NSD3, which belongs to a subfamily of H3K36 methyltransferases. Unexpectedly, AML cells were foun...
ORGANISM(S): Mus musculus 
2015-12-17 | E-GEOD-71183 | biostudies-arrayexpress
TranscriptomicsNSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler (RNA-Seq)
The bromodomain and extraterminal (BET) protein BRD4 is a therapeutic target in acute myeloid leukemia (AML). Here, we demonstrate that the AML maintenance function of BRD4 requires its interaction with NSD3, which belongs to a subfamily of H3K36 methyltransferases. Unexpectedly, AML cells were foun...
ORGANISM(S): Mus musculus 
2015-12-17 | E-GEOD-71185 | biostudies-arrayexpress
UnknownA NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells.
Not available
S-EPMC8882712 | biostudies-literature
GenomicsThe histone methyltransferase NSD3 enhances rDNA transcription in cancer
The histone methyltransferase NSD3 enhances rDNA transcription in cancer
PRJNA930738 | ENA
GenomicsElevated NSD3 Histone Methylation Activity Drives Squamous Cell Lung Cancer
Elevated NSD3 Histone Methylation Activity Drives Squamous Cell Lung Cancer
PRJNA627861 | ENA
GenomicsGene expression profile of U2-OS control and NSD3 knockdown cells
Gene expression profile of U2-OS control and NSD3 knockdown cells
PRJNA484629 | ENA
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