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GenomicsDissection of cMyc+ GC-B cells
Dissection of cMyc+ GC-B cells
PRJNA612687 | ENA
TranscriptomicsThe long noncoding RNA PCAT-1 promotes prostate cancer cell proliferation through post-transcriptional stabilization of the cMyc oncogene
Transcriptional profiling of Du145-PCAT1 and RWPE-PCAT1 cells treated with either non-targeting siRNA or two independent siRNAs targeting cMyc. The goal was to determine the role of cMyc in mediating PCAT-1 transcriptional regulation. Three-condition experiment, PCAT1 cells with non-targeting siRNA ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-54872 | biostudies-arrayexpress
ProteomicsAn NSD3-targeting PROTAC suppresses the NSD3 and cMyc oncogenic nodes in cancer cells
Nuclear receptor binding SET domain protein 3 (NSD3), a gene located within the 8p11-p12 amplicon frequently detected in cancers, encodes a chromatin modulator and an attractive onco-target. However, agent that can effectively suppress the NSD3-mediated oncogenic actions is currently lacking. We rep...
ORGANISM(S): Homo sapiens (Human) 
2021-08-27 | PXD021901 | Pride
Histone Chromatin Nsd3 Epigenetics Cmyc Protac Degrader 
GenomicsDissection of cMyc+ GC-B cells at single-cell level
Dissection of cMyc+ GC-B cells at single-cell level
PRJNA533063 | ENA
GenomicsTranscriptome changes in human endothelial cells with reduced cMYC signaling.
Transcriptome changes in human endothelial cells with reduced cMYC signaling.
PRJNA679567 | ENA
ProteomicsPLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and cMyc signaling pathways
Melanoma, originating from the malignant transformation of melanocytes, is the deadliest form of skin cancer. The incidence of primary cutaneous melanoma is increasing, with about 132,000 new cases annually. While early-stage melanoma can often be treated successfully with surgery, advanced melanoma...
ORGANISM(S): Homo sapiens (Human) 
2025-01-22 | PXD053608 | Pride
Cmyc Mapk Plekha4 Apoptosis 
ProteomicsNon-metabolic PHGDH facilitates cMyc to urge advanced liver cancer
Metabolic dysregulation is an important feature of malignant tumors. Serine synthesis pathway (SSP) reshapes tumor cells to enhance their growth and survival capabilities, especially under serine starvation. However, whether and how SSP is involved in the progression of liver cancer has not been cle...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD017809 | Pride
Serine synthesis Hepatocellular carcinoma Phgdh Proteome 
TranscriptomicsGene expression analysis of cMyc-deficient CD8 T cells retrovirally overexpressing cMyc or AP4
To determine functional overlap between cMyc and AP4 in CD8+ T cell priming, we retrovirally expressed cMyc or AP4 in cMyc-deficient CD8+ T cells and examined gene expression after activation.
ORGANISM(S): Mus musculus 
2014-07-13 | GSE58079 | GEO
UnknownAssociation of CMYC polymorphisms with hepatoblastoma risk.
Not available
S-EPMC8798278 | biostudies-literature
UnknownRole of HNF4alpha-cMyc interaction in liver regeneration after partial hepatectomy.
Not available
S-EPMC11322135 | biostudies-literature
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