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GenomicsNuclear receptor Nur77 regulates immunomechanics of macrophages
Nuclear receptor Nur77 regulates immunomechanics of macrophages
PRJNA1065503 | ENA
TranscriptomicsNuclear receptors Nur77 and Nurr1 modulate mesenchymal stromal cell migration
Expression analysis of migrating and non-migrating mesenchymal stromal cells (MSC) in fetal bone marrow Keywords: fetal bone marrow, mesenchymal stromal cells, migration, gene expression, genomics Three biological replates for both migrating and non-migrating mesenchymal stromal cells (MSC) in feta...
ORGANISM(S): Homo sapiens 
2011-10-23 | E-GEOD-24892 | biostudies-arrayexpress
TranscriptomicsNur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance
The nuclear orphan receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to exhibit an anti-inflammatory function in macrophages. To further elucidate the role of Nur77 in macrophage physiology, we compared the transcriptome of bone marrow-derived macrophages (BMM) from wild-type (WT) and Nur77-knoc...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-68167 | biostudies-arrayexpress
ProteomicsNur77 resolves the inflammatory response of macrophages primarily by cis- and trans-regulation of AP-1 target genes
Nuclear receptor Nur77 plays a crucial, protective role in chronic inflammation. In activated macrophages, deficiency of Nur77 has been shown to result in excessive pro-inflammatory cytokine secretion. Previous research suggested that Nur77's regulatory function in inflammation is due to repression ...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD054271 | Pride
Lc-ms/ms Nr4a1 Ap-1 Macrophage Inflammation 
TranscriptomicsEffect of Nur77 on gene expression in white adipose tissue of fasted mice.
The aim was to study the effects of Nur77 on the white adipose tissue transcriptome after fasting. For this purpose we performed gene expression profiling of white adipose tissue from Nur77-/- mice and wildtype (Nur77+/+) littermates submitted to prolonged fasting using microarray analysis on >27k e...
ORGANISM(S): Mus musculus 
2012-11-09 | E-MEXP-3771 | biostudies-arrayexpress
GenomicsNuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages [ChIP-seq]
Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages [ChIP-seq]
PRJNA1096698 | ENA
GenomicsNuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages [RNA-seq]
Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages [RNA-seq]
PRJNA1096697 | ENA
GenomicsGenome-wide binding profiles of nuclear FGFR1, RXR? and Nur77 in pluripotent mouse Embryonic Stem Cells and during Retinoic Acid-induced differentiation
We report the genome-wide binding patterns of nuclear FGFR1, RXR? and Nur77 in pluripotenet mESC and as mESC differentiate towared a neuronal lineage in response to high levels of Retinoic Acid treatment in vitro. We also report the genome-wide incorporation of histone varant H3.3 into chromatin spe...
ORGANISM(S): Mus musculus 
2015-05-01 | E-GEOD-65695 | biostudies-arrayexpress
GenomicsDisease correlation mapping based discovery of 2-methoxyestradiol as an endogenous ligand of the orphan nuclear receptor Nur77
Disease correlation mapping based discovery of 2-methoxyestradiol as an endogenous ligand of the orphan nuclear receptor Nur77
PRJNA1185259 | ENA
UnknownOrphan nuclear receptor Nur77 regulates androgen receptor gene expression in mouse ovary.
Not available
S-EPMC3386274 | biostudies-literature
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