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ProteomicsNucleolar beacon for monitoring nucleolar morphology and proteomics in living cells
A novel approach combined nucleolar beacon with proximity labeling to obtain the nucleolar proteome. These techniques offer effective tools for investigating nucleolar functions in living cells and present a potential application method for drug delivery.
ORGANISM(S): Homo sapiens (Human) 
2025-06-23 | PXD059125 | Pride
Nucleolar proteomics nucleolar beacon proximity labeling 
UnknownProteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.
Not available
S-EPMC2758753 | biostudies-literature
UnknownNucleolar Proteomics Revealed the Regulation of RNA Exosome Localization by MTR4.
Not available
S-EPMC12356310 | biostudies-literature
TranscriptomicsSmall RNA deep sequencing of cellular subcompartments
RNA deep sequencing efforts have revealed abundant expression of small RNAs derived from small nucleolar (sno) RNAs. We employ here spatial RNA deep sequencing to assess the expression of 10-40 nt small RNAs in subcellular compartments of HeLa cells. Total cellular, cytoplasmic, nuclear and nucleola...
ORGANISM(S): Homo sapiens 
2014-05-07 | E-GEOD-50057 | biostudies-arrayexpress
ProteomicsDifferential analysis of nucleolar proteomics in triple negative breast cancer
Breast cancer is one of the most common cancers in women. Of the different subtypes of breast cancer, the triple negative breast cancer subtype of breast cancer is the most aggressive. A proteomic screen of nucleolar content across breast cancer subtypes found that triple negative breast cancer cell...
ORGANISM(S): Homo sapiens (Human) 
2021-03-05 | PXD021201 | Pride
Breast cancer Tnbc Nucleolar proteome Nucleolus Breast cancer subtypes 
UnknownNucleolar beacon for monitoring nucleolar morphology and proteomics in living cells.
Not available
S-EPMC12154232 | biostudies-literature
ProteomicsDifferential analysis of nucleolar proteomics in metastatic breast cancer
The nucleolus, responsible for ribosome biogenesis, acts as a key center for detecting and responding to cellular stress. Additionally, growing evidence suggests that ribosome biogenesis may play a significant role in promoting metastasis. A proteomic screen of nucleolar protein content between meta...
ORGANISM(S): Homo sapiens (Human) 
2025-07-27 | PXD060687 | Pride
Nucleolus Breast cancer Metastasis 
ProteomicsProteomic profile of oxaliplatin treated cell line reveals DNA damage induced nucleolar stress as main response.Proteomic profile of oxaliplatin treated cell line reveals DNA damage induced nucleolar stress as main response
Oxaliplatin is a widely used anti-cancer drug. It is part of treatment regimens for colorectal and pancreatic cancers, but it is tested in esophageal, biliary tract, gastric or hepatocellular cancers as well. Contrary to this wide application, there is only limited amount of information about oxalip...
ORGANISM(S): Homo sapiens (Human) 
2017-05-11 | PXD003543 | Pride
Proteomics Oxaliplatin Lc-ms Ribosomal stress Nucleolar stress 
UnknownNucleolar proteomics identifies S100A16 as a key nucleolar protein driving breast cancer metastasis.
Not available
S-EPMC12373912 | biostudies-literature
ProteomicsNucleolar proteome of the developing brain
To study nucleolar involvement in brain development, the nuclear and nucleolar proteomes from the rat cerebral cortex at postnatal day 7 were analyzed using LC-MS/iTRAQ methodology.
ORGANISM(S): Rattus norvegicus (Rat) 
2016-04-11 | PXD002188 | Pride
Lc-ms Rat Nucleolus Itraq 
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