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TranscriptomicsGenome-wide analysis of gene expression regulated by nucleolin in mouse embryonic stem cells
To further explore the function and underlying mechanism of nucleolin in embryonic stem cells (ESCs), we compared the transcription profile of tetracycline (Tc)-inducible EGFP (as a control) or nucleolin siRNA expression-stable ESCs cultured with or without Tc for 3 days, and identified distinct cla...
ORGANISM(S): Mus musculus 
2011-10-19 | E-GEOD-23993 | biostudies-arrayexpress
TranscriptomicsiCLIP Analysis of WT, phospho-defective, and phospho-mimicking mutants of mouse Nucleolin in iKras PDAC cells
This experiment aimed to identify Nucleolin (Ncl) binding sites on a transcriptome-wide scale, by performing iCLIP in mouse iKras PDAC cells (Ying et al., 2012) transiently transfected with a mammalian expression construct encoding a wild-type (WT) myc-Ncl, a phospho-defective mutant in which S28, S...
ORGANISM(S): Mus musculus 
2023-03-01 | E-MTAB-12481 | biostudies-arrayexpress
ProteomicsNuclear nucleolin interactome analysis
Nucleolin (NCL) is a major component of the cell nucleolus, which has the ability to rapidly shuttle to several other cell’s compartments. NCL has been shown to play important roles in a variety of essential functions among which ribosome biogenesis, gene expression and cell growth. However, the pre...
ORGANISM(S): Homo sapiens (Human) 
2016-04-11 | PXD003554 | Pride
Tandem affinity purification Nucleolin Nanolc-ms/ms 
ProteomicsNucleolin is a cell surface receptor of C1QTNF4
C1QTNF4 is a secreted protein that is structurally unique within the C1QTNF family, a family of proteins that have structural homology with both complement C1q and the tumor necrosis factor superfamily. The role of C1QTNF4 in immunity and inflammation remains poorly defined and a cell surface recept...
ORGANISM(S): Homo sapiens (Human) 
2021-03-21 | PXD023088 | Pride
Innate immunity Nucleolin Cell surface receptor Inflammation Ctrp4 C1qtnf4 Monocyte Autoimmune disease Systemic lupus erythematosus 
GenomicsGene expression of nucleolin or TRA2B4-silencing HCT116 cells
Gene expression of nucleolin or TRA2B4-silencing HCT116 cells
PRJNA448909 | ENA
GenomicsAnalysis of RNA localization in nucleolin deficient axons
Analysis of RNA localization in nucleolin deficient axons
PRJNA595902 | ENA
TranscriptomicsIn vivo NCL-targeting affects breast cancer aggressiveness through miRNA regulation [Affymetrix]
Numerous studies have described the altered expression and the causal role of miRNAs in human cancer. However, to date efforts to modulate miRNA levels for therapeutic purposes have been challenging to implement. Here, we find that Nucleolin (NCL), a major nucleolar protein, post-transcriptionally r...
ORGANISM(S): Homo sapiens 
2012-11-02 | E-GEOD-41972 | biostudies-arrayexpress
GenomicsBinding of Nucleolin to HBV cccDNA
Binding of Nucleolin to HBV cccDNA
PRJNA509631 | ENA
GenomicsRIP-seq reveals the interactome of nucleolin in activated CD4+ T cells
RIP-seq reveals the interactome of nucleolin in activated CD4+ T cells
PRJNA1099297 | ENA
GenomicsEffect of nucleolin-binding aptamer AS1411 on gene expression in 3T3 cells
Effect of nucleolin-binding aptamer AS1411 on gene expression in 3T3 cells
PRJNA1147748 | ENA
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