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ProteomicsCross-species proteomic comparison of whole cell lysates, outer membrane vesicles and membrane fractions of Francisella tularensis subsp. tularensis versus subsp. holarctica
Secretion of outer membrane vesicles (OMV) presents an important phenomenon in Gram-negative bacteria and they play multiple roles in their lifestyle including virulence and host-pathogen interaction. Francisella tularensis secretes unusually shaped tubular OMV. We here present a proteomic compariso...
ORGANISM(S): Francisella tularensis Francisella tularensis subsp. tularensis SCHU S4 Francisella tularensis subsp. holarctica FSC200 
2021-02-08 | PXD022406 | Pride
Q-exactive Schus4 Outer membrane vesicles Fsc200 Cross-species proteomic comparison Francisella tularensis 
ProteomicsCharacterization of the O-Glycoproteome of Prevotella intermedia
Prevotella intermedia is a Gram-negative bacterium belonging to the Bacteroidetes phylum and is notably linked to periodontitis. Several other species within this phylum have been reported to possess the general O-glycosylation system, and the O-glycoproteome has been well characterized in Tannerell...
ORGANISM(S): Prevotella intermedia ATCC 25611 = DSM 20706 
2024-02-14 | PXD047143 | Pride
Outer membrane vesicles O-glycosylation Bacteroidetes Type ix secretion system 
ProteomicsProteomic characterization and label-free comparison of outer membrane vesicles from Francisella tularensis subsp. holarctica strain FSC200 isolated from different cultivation conditions
Francisella tularensis is a Gram-negative, facultative intracellular bacterium, causing a severe disease known as tularemia. It is known to secrete unusually shaped nanotubular outer membrane vesicles (OMV) loaded with number of virulence factors and immunoreactive proteins. In this study the nanotu...
ORGANISM(S): Francisella tularensis subsp. holarctica Francisella tularensis subsp. holarctica FSC200 
2019-09-30 | PXD013074 | Pride
Francisella tularensis  fsc200  outer membrane vesicles  stress response 
ProteomicsWild-type and single-O-antigen repeat outer-membrane vesicles induce equivalent protection against homologous and heterologous Salmonella challenge
Lipopolysaccharide O-antigen is an immunodominant target of protective antibodies. Variation in O-antigen structures limits antibody-mediated cross-protection between closely-related pathogens including Salmonella Typhimurium (STm) and S. Enteritidis (SEn). Bacterial outer membrane vesicles (OMV) ar...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028s Wu 
2025-02-21 | PXD056628 | Pride
Outer-membrane_vesicles Omv O-antigen Salmonella 
Proteomicso Differential temporal release and lipoprotein loading in B. thetaiotaomicron bacterial extracellular vesicles
o Bacterial extracellular vesicles (BEVs) contribute to stress responses, quorum sensing, biofilm formation, and interspecies and interkingdom communication. However, the factors that regulate their release and heterogeneity are not well understood. We set out to investigate these factors in the com...
ORGANISM(S): Bacteroides thetaiotaomicron 
2024-01-22 | PXD043651 | Pride
O outer membrane vesicles  omv  bacterial extracellular vesicles  bev  bacteroides 
ProteomicsLC-MS of migrasomes and vesicles form human ccRCC 786-O cells
On one hand, we performed label-free quantitative proteomics to analyze migrasome proteins derived from 786-O cells vs ITM2B-knockdown 786-O cells.On the other hands,we isolated ITM2B truncation-containing vesicles and performed mass proteomic analysis to identify proteins that were carried by ITM2B...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD054746 | Pride
Migrasome Vesicle Ccrcc 
UnknownOuter-inner membrane vesicles naturally secreted by gram-negative pathogenic bacteria.
Not available
S-EPMC4291224 | biostudies-literature
UnknownUltrastructural and glycoproteomic characterization of Prevotella intermedia: Insights into O-glycosylation and outer membrane vesicles.
Not available
S-EPMC10897501 | biostudies-literature
UnknownOuter membrane vesicles of Tannerella forsythia: biogenesis, composition, and virulence.
Not available
S-EPMC4604654 | biostudies-literature
MetabolomicsMetabolic-engineered probiotic-OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy

Chronic, drug-resistant bone infection caused by methicillin-resistant Staphylococcus aureus (MRSA) features an immunosuppressive niche enabling persistent infection and impaired bone healing. Specific treatment requires initial antibacterial immune activation against infection, followed by resha...

2026-03-19 | MTBLS14091 | MetaboLights
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