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ProteomicsHuman OCIAD2 binding partners and the effect of OCIAD2 depletion on mitochondrial protein levels
Assembly of the oxidative phoshorylation dimeric complex III (CIII2) in the mitochondrial inner membrane is an intricate process in which many factors are involved. Despite many studies this process is yet to be completely understood. Here we report the identification of human OCIAD2 (Ovarian Carcin...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD023025 | Pride
Oxidative phosphorylation Mitochondria Ociad2 Oxphos complex iii 
GenomicsOCIAD2 promotes epithelial to mesenchymal transition during mesendoderm specification of human pluripotent stem cells
OCIAD2 promotes epithelial to mesenchymal transition during mesendoderm specification of human pluripotent stem cells
PRJNA1321888 | ENA
TranscriptomicsOCIAD2 promotes epithelial to mesenchymal transition during mesendoderm specification of human pluripotent stem cells
The mitochondrial protein OCIAD2 is misexpressed in several cancers and neurodegenerative diseases. However, insights into its physiological role, particularly in the context of stem cell differentiation, remain unexplored. Our analyses report that OCIAD2 is expressed in undifferentiated human embry...
ORGANISM(S): Homo sapiens 
2026-08-03 | GSE307502 | GEO
UnknownOCIAD2 Promotes Cancer Progression via Metabolic Reprogramming in Lung Adenocarcinoma.
Not available
S-EPMC12323000 | biostudies-literature
UnknownOCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma.
Not available
S-EPMC6248579 | biostudies-literature
UnknownOCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin.
Not available
S-EPMC11113593 | biostudies-literature
ProteomicsMapping perturbations in the cellular proteome of OCIAD1 and OCIAD2 knockdown U2OS cells.
To gain insight into the function of both OCIAD paralogs, we used untargeted quantitative mass spectrometry to compare the whole-cell proteomes of control U2OS cells, U2OS cells with individual or double OCIAD1/OCIAD2 knockdown, and OCIAD1 knockdown cells in which OCIAD1 expression was reintroduced ...
ORGANISM(S): Homo sapiens (Human) 
2021-05-14 | PXD025573 | Pride
Ociad2 Knockdown Cytochrome c1 Ociad1 Mitochondria Complex iii 
UnknownA double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation.
Not available
S-EPMC5943604 | biostudies-literature
UnknownOvarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III-specific assembly factor in mitochondria.
Not available
S-EPMC9250361 | biostudies-literature
UnknownOCIAD2 as a novel prognostic and therapeutic biomarker for pancreatic cancer: A study based on transcriptomic signature and bioinformatics analysis.
Not available
S-EPMC12517509 | biostudies-literature
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