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We used hydrogen-deuterium exchange mass spectrometry (HDX-MS) to investigate the influence of OEA on HIF-3A-ARNT.HDX-MS data indicated that OEA binding stabilized multiple residues within the Gβ and Fα regions of HIF-3A PAS-B domain.It is possible that the stabilized Gβ and Fα function as an “inter...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD033376 | Pride
Genomics
Effect of OEA on gut microbiota in mice
Effect of Oleoylethanolamide (OEA) Compared to a Placebo on the Gut Microbiome in an Adult Population
An Affimetrix GeneChip Human Genome U133 Plus 2.0 Array was used to study the effect of oleoylethnolamide on gene expression. The addition of 0.01 mM oleoylethanolamide (OEA) to human subcutaneous adipocytes significantly affected the expression of 1013 genes, with 556 being up-regulated and 457 bei...
ORGANISM(S): Homo sapiens 
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