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ProteomicsOestrogen Activates the MAP3K1 Cascade and -catenin to Promote Granulosa-Like Cell Fate in a Human Testis-Derived Cell Line
: Sex determination triggers the differentiation of the bi-potential gonad into either an ovary or testis. In non-mammalian vertebrates, the presence or absence of oestrogen dictates gonad differ-entiation, while in mammals, this mechanism has been supplanted by the testis determining SRY gene. Exog...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026927 | Pride
Oestrogen Sox9 Map3k1 Beta-catenin 
TranscriptomicsTranscription profiling of human primary neuronal cell cultures after of oestrogen treatment
The purpose of this experiment was to identify oestrogen regulated genes in human primary cell cultures of neuronal cells modelling the developing human nervous system. We were especially interested in genes involved in proliferation, differentiation and migration of neuronal cells and genes involve...
ORGANISM(S): Homo sapiens 
2009-12-05 | E-GEOD-17645 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MCF7 cells in oestrogen treatment time course.
Expression analysis in human MCF7 cells after 3h, 6h or 12h of oestrogen treatment
ORGANISM(S): Homo sapiens 
2010-03-08 | E-MTAB-158 | biostudies-arrayexpress
TranscriptomicsOestrogen effects on the left ventricular transcriptome of healhty mice
Comparison of mouse left ventricular responses to oestrogen with control.
ORGANISM(S): Mus musculus 
2014-04-10 | E-MEXP-3834 | biostudies-arrayexpress
GenomicsComparing oestrogen-responsive genes in endometrial and breast cancer cell lines
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines
PRJNA421096 | ENA
GenomicsOestrogen promotes innate immune invasion of Candida albicans through inactivation of complement
Oestrogen promotes innate immune invasion of Candida albicans through inactivation of complement
PRJNA606507 | ENA
TranscriptomicsComparing oestrogen-responsive genes in endometrial and breast cancer cell lines
Up to 80% of endometrial and breast cancers express the oestrogen receptor ERa. Unlike breast cancer, anti-oestrogen therapy has had limited success in endometrial cancer, raising the possibility that oestrogen has different effects in the two cancer types. We investigated the role of oestrogen in e...
ORGANISM(S): Homo sapiens 
2018-08-29 | GSE107693 | GEO
GenomicsImpact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation
Presurgical studies allow study of the relationship between mutations and response of estrogen receptor positive (ER+) breast cancer to aromatase inhibitors (AIs) but have been limited to small biopsies. Here in Phase I of this study, we perform exome sequencing on baseline, surgical core-cuts and b...
EGAS00001001940 | EGA
TranscriptomicsTranscription profiling of human angiomyolipoma xenograft tumours grown in mice after estrogen treatment
SV7tert AML cells were obtained from ATCC and cultured in Dulbecco's modified essential medium (DMEM), glutamine (4mmol) and 10% foetal bovine serum (FBS). Two million SV7tertAML cells were subcutaneously injected into nude mice either with or without subcutaneous oestrogen pellets (n=4 per group);...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5868 | biostudies-arrayexpress
TranscriptomicsOestrogen promotes innate immune invasion of Candida albicans through inactivation of complement
Candida albicans is a commensal of the urogenital tract and the predominant cause of vulvovaginal candidiasis (VVC). Roughly, 70% of otherwise healthy women succumb to VVC at least once in their life time. Elevated oestrogen levels are associated with C. albicans colonisation of the vagina and sympt...
ORGANISM(S): Candida albicans 
2022-01-04 | GSE145240 | GEO
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