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MetabolomicsSystematic analyses of lipid mobilization by human lipid transfer proteins

Lipid transfer proteins (LTPs) maintain the specialised lipid compositions of biological membranes, and many are associated with disease. In eukaryotes, they support organellar functions by transporting lipids between compartmentalised metabolic pathways. However, for the majority of the hundreds...

2025-11-14 | MTBLS9567 | MetaboLights
ProteomicsIntegrative organelle-based functional proteomics in ARSACS-focus on bioenergetics and autophagy
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an inherited neurodegenerative disease characterized by early-onset spasticity in the lower limbs, axonal-demyelinating sensorimotor peripheral neuropathy, and cerebellar ataxia. Our understanding of the genetic basis, protein fun...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-20 | MSV000088592 | MassIVE
TranscriptomicsGene expression in cell cycle of Cyanidioschyzon merolae_1
To analyze mitotic cycle and organelle proliferation cycle, we investigated C.merolae cells across two cell cycles synchronized by light and dark cycles. C.merolae has one nucleus, mitochondria and chloroplast (Kuroiwa et al,1993. Protoplasma). Their division are strictly regulated by cell cycle and...
ORGANISM(S): Cyanidioschyzon merolae 
2010-05-19 | E-GEOD-8268 | biostudies-arrayexpress
TranscriptomicsComparative analysis of transcripts from mia40-4int mutant and wild-type Saccharomyces cerevisiae strains quantified in RNA-seq experiment
The vast majority of the mitochondrial proteome originates from nuclear genes and is transported into the organelle after synthesis in the cytosol. Complex machineries, which maintain the specificity of protein import and sorting exist. Dysfunctions of mitochondrial protein sorting pathways result i...
ORGANISM(S): Saccharomyces cerevisiae 
2015-07-31 | E-MTAB-3588 | biostudies-arrayexpress
ProteomicsCitrullinated proteins in monocyte organelle fractions
Citrullinated proteins found in the organelle fractions of monocytes incubated in calcium
ORGANISM(S): Homo sapiens (Human) 
2023-10-03 | PXD044188 | Pride
Human Mass spectrometry Citrullination Monocytes 
ProteomicsSpatial and temporal proteomic of HCMV-infected cells
Project for the study of spatial and temporal alterations in organelle proteins during HCMV infection. Two datasets are included, one for label-free quantification and one for TMT quantification. Samples were collected at 5 time points of infection (24, 48, 72, 96, and 120 hours) and subject to orga...
ORGANISM(S): Homo sapiens (Human) Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) 
2016-09-27 | PXD003925 | Pride
Hcmv spatial organelle temporal cytomegalovirus fibroblasts 
ProteomicsComparative analysis of the human and mouse placental transcriptome and proteome
An important question for the use of the mouse as a model for studying human disease is the degree of functional conservation of genetic control pathways from human to mouse. The human and mouse placenta show structural similarities but there have been no systematic attempt to assess their molecular...
ORGANISM(S): Mus musculus 
2009-06-29 | E-GEOD-13299 | biostudies-arrayexpress
ProteomicsTic20-like proteins mediate organelle assembly in Alphaproteobacteria
Organelle-specific protein translocation systems are essential for the biogenesis of many organelles in eukaryotes but thought to be absent from prokaryotic organelles like magnetosomes. Here, using evolutionary analyses, we show that magnetosomal MamF-like proteins represent members of the widespre...
ORGANISM(S): Magnetospirillum gryphiswaldense 
2024-11-19 | PXD032959 | Pride
Mart Magnetosomes Organelles Protein translocation Mamj Tic20 Duf4870 Magnetokeleton 
ProteomicsFunctional partitioning of a liquid-like organelle during assembly of axonemal dyneins
The associated files are the results of AP-MS experiments done from Xenopus multiciliated cells derived from dissected animal caps. Baits used for affinity purification were GFP-dnai2, GFP-wdr78, and GFP-C16orf71. Note that some files associated with the C16orf71 experiments may be mislabeled C16o...
ORGANISM(S): Xenopus Laevis (ncbitaxon:8355) 
2020-03-10 | MSV000085075 | MassIVE
ProteomicsProteomics identifies organelle specific phosphorylation and reveals major subcellular reorganization in the progression of NAFLD
Obesity induced non-alcoholic fatty liver disease (NAFLD) is associated with the development of type 2 diabetes and constitutes a major health problem. A hallmark of the diseases is extensive lipid droplet (LD) formation and accumulation of toxic lipid species interfering with cellular signaling and...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-29 | PXD007653 | Pride
Organelle protoemics Liver Diabetes Steatosis 
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