Phosphorylation of histone H3 at Serine 10 emerges as a mechanism increasing chromatin accessibility of the transcription factor NF-kB for a particular set of immune genes. Here we report that a bacterial pathogen uses this strategy to shape the transcriptional response of infected host cells. We id...
Phosphothreonine lyases are a small family of bacterial virulence factors secreted into host cells during infection by certain Gram-negative pathogens. This family of enzymes is known for its unique mechanism of silencing host immune signaling via the irreversible β-elimination of phosphothreonine (...
This dataset corresponds to timecourses of treatment of a pervandate-treated HEK293T phosphoproteome-derived peptide library with the bacterial phospholyases OspF, SpvC, HopAI, or OspF(residues 25-239).
