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TranscriptomicsTranscriptional profiling of the Borrelia burgdorferi bb0647 mutant
RNA was isolated from late-log pahse wild-type Borrelia burgdorferi B31 and the bb0647 mutant grown in BSKH media at 37 degree, 5% CO2. cDNA was synthesized, labeled and hybridized to the 70mer oligonucleotide B. burgdorferi array. Slides were scanned using axon scanner and image were analyzed using...
ORGANISM(S): Borrelia burgdorferi 
2010-05-15 | E-GEOD-17422 | biostudies-arrayexpress
ProteomicsProteomic data were obtained from hydrogenotrophic methanogen strain isolated from the rumen of sheep under methanogenesis-inhibiting conditions, providing a resource to interrogate protein-level adjustments and methane-associated pathways during inhibitor exposure in assays.
Proteomic data were obtained from hydrogenotrophic methanogen strain isolated from the sheep rumen under methanogenesis-inhibiting conditions, providing a resource to interrogate protein-level adjustments and methane-associated pathways during inhibitor exposure. The dataset enables analyses of diff...
ORGANISM(S): Methanobrevibacter olleyae 
2026-03-04 | PXD070174 | Pride
TranscriptomicsComparison between Borrelia burgdorferi wild type strain and cognate rpoS, rpoN and rrp2 mutants
The RpoN-RpoS alternative sigma factor pathway is essential for key adaptive responses by Borrelia burgdorferi, particularly those involved in the infection of a mammalian host. A putative response regulator, Rrp2, ostensibly is required for activation of the RpoN-dependent transcription of rpoS. ...
ORGANISM(S): Borrelia burgdorferi 
2008-09-09 | E-GEOD-11284 | biostudies-arrayexpress
ProteomicsTupaia chinensis hippocampus LC-MS/MS
Tree age groups of T.chinensis–15 days, 3 months and 1.5 years – were selected to study their hippocampal protein expression profiles.
ORGANISM(S): Tupaia chinensis 
2023-03-11 | PXD039177 | Pride
Hippocampus Tupaia chinensis Lc-ms/ms 
UnknownCharacterization of immune microenvironment infiltration and m6A regulator-mediated RNA methylation modification patterns in osteoarthritis.
Not available
S-EPMC9728527 | biostudies-literature
TranscriptomicsExpression data from a new FACS approach isolated hESC derived endoderm cells using transcription factors
We show that high quality microarray gene expression profiles can be obtained following FACS sorting of cells using combinations of transcription factors. We use this transcription factor FACS (tfFACS) methodology to perform a genomic analysis of hESC-derived endodermal lineages marked by combinatio...
ORGANISM(S): Homo sapiens 
2011-08-23 | E-GEOD-24135 | biostudies-arrayexpress
ProteomicsPyroptosis therapy targeting TNBC
Biomimetic nanococrystals are prepared using the preferred combination of mitoxantrone and gambogic acid for rational drug delivery. The unique mechanism of obtained nanococrystals regulating pyroptosis genes through ribosomal stress is revealed by TMT-proteomics of 4T1 cells.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD053939 | Pride
Mice，4t1 cells，lc-ms/ms 
UnknownRNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Not available
S-EPMC5490984 | biostudies-literature
ProteomicsMass spectrometry data of Platelet-rich plasma from 6 young and 6 elderly individuals
We prepared platelet-rich plasma from the blood of 6 young volunteers and 6 elderly volunteers, respectively, and removed 95% of high-abundance proteins, followed by mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-04-24 | PXD050061 | Pride
Proteomics Tissue repair Aging Platelet-rich plasma 
TranscriptomicsAltered interactions between the gut microbiome and colonic mucosa precede polyposis in APCMin/+ mice
Mutation of the adenomatous polyposis coli (APC gene), an early event in the adenoma-carcinoma sequence, is present in 70-80% of sporadic human colorectal adenomas and carcinomas. To test the hypothesis that mutation of the APC gene alters microbial interactions with host intestinal mucosa prior to...
ORGANISM(S): Mus musculus 
2015-08-24 | E-GEOD-67634 | biostudies-arrayexpress
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