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Candidatus Liberibacter asiaticus (CLas), the causative agent of Citrus Huanglongbing (HLB), disrupts global citrus production through poorly defined mechanisms. Integrated proteomic and ubiquitinomic analyses of CLas-infected Citrus sinensis leaves revealed systemic proteostatic dysregulation. Prot...
ORGANISM(S): Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis) 
2026-09-14 | PXD062872 | Pride
Biomimetic nanococrystals are prepared using the preferred combination of mitoxantrone and gambogic acid for rational drug delivery. The unique mechanism of obtained nanococrystals regulating pyroptosis genes through ribosomal stress is revealed by TMT-proteomics of 4T1 cells.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD053939 | Pride
O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is the sole enzyme that catalyzes all O-GlcNAcylation reactions intracellularly. Previous investigations have found that OGT levels oscillate during the cell division process. Specifically, OGT abundance is downregulated during mitosis, but...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050552 | Pride
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