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TranscriptomicsTranscription profiling of Bos taurus granulosa and theca cells during ovarian antral follicle development.
Coordinated interactions between ovarian granulosa and theca cells are required for female endocrine function and fertility. To elucidate these interactions the regulation of the granulosa and theca cell transcriptomes during bovine antral follicle development were investigated. Granulosa cells and ...
ORGANISM(S): Bos taurus 
2008-11-04 | E-GEOD-11495 | biostudies-arrayexpress
ProteomicsQuantitative Label-free Proteomic Analysis of Ovarian Antral Follicles Exposed In Vivo to a Mixture of Phthalates
Dibutyl phthalate (DBP), di-2-ethylhexyl phthalate (DEHP), and benzyl butyl phthalate (BBP) are three phthalates commonly found in consumer products, including the plastic coating of pharmaceuticals and personal care products. Folliculogenesis, a tightly regulated process occurring in the ovary, is ...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-18 | PXD047061 | Pride
Phthalates Ovarian antral follicles 
TranscriptomicsGene expression in bovine ovarian follicle theca interna
Thecal tissue forms a layer around the follicle just prior to antral stage and grows with the follicle (containing an oocyte) as it matures. The innermost component (theca interna) supplies hormones and other factors necessary to the growth and development of the granulosa and oocyte. Most follicles...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-49505 | biostudies-arrayexpress
TranscriptomicsGene expression in bovine ovarian follicle granulosa
Granulosa cells mature and die as ovarian follicles enlarge and die (undergo atresia) under the influence of hormones and intrafollicular factors. Later in follicular development, a fluid-filled antrum is formed, a process which is accompanied by a high rate of atresia. These small antral follicles ...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-39589 | biostudies-arrayexpress
ProteomicsProteome of fluid from human small antral follicles reveals insights in folliculogenesis and oocyte maturation.
Human ovarian follicles develop a fluid-filled antrum when they reach a diameter of around 250 µm. The antrum contains follicular fluid (FF) composed of secretions from cells in the follicle and from circulation. The composition of FF undergoes massive changes in relation to follicular development. ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013344 | Pride
Follicles Proteomics Human Folliculogenesis Follicular fluid 
ProteomicsProteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation.
Follicles of polycystic ovaries (PCO) often become arrested in early antral stages at around 3 to 11 mm in diameter. The condition disturbs dominant follicle selection and may result in altered ovulation and anovulation. During the growth and development of human follicles, the follicular fluid (FF)...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD031485 | Pride
Proteomics Oocyte maturation. Small antral follicles Follicular fluid 
ProteomicsProteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation.
Protein composition of human ovarian follicular fluid (FF) constitutes the microenvironment for oocyte development. Several proteomics studies of FF from pre-ovulatory follicles have revealed insights on oocyte maturation, however, there is a lack of knowledge on changes produced at protein levels i...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021338 | Pride
Proteomics Oocyte maturation. Small antral follicles Follicular fluid 
TranscriptomicsCharacterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid of Developing Bovine Antral Follicles
Exosomes and microvesicles (i.e., extracellular vesicles; EVs) have been identified within ovarian follicular fluid, and recent evidence suggests that EVs are able to elicit profound effects on ovarian cell function. While existence of miRNA within EVs has been reported, it remains unknown if EV si...
ORGANISM(S): Bos taurus 
2016-02-09 | E-GEOD-74879 | biostudies-arrayexpress
MetabolomicsUHPLC-OE-MS metabolic profile of follicular fluid in patients with ovarian endometriosis: a pilot study of an endometriosis cohort

BACKGROUND: Endometriosis is a common benign gynaecological disorder. A number of studies have confirmed that the occurrence of disease in endometriosis patients is associated with metabolic changes in biological fluids and tissues. We set out to investigate the metabolic charact...

2024-02-20 | MTBLS8621 | MetaboLights
TranscriptomicsTranscription profiling of rat folliculogenesis reveals glial derived neurotrophic factor promotes ovarian primordial follicle development
Female fertility is determined in part by the size and development of the primordial follicle pool. The current study investigates the role of glial cell-line derived neurotrophic factor (GDNF) in the regulation of primordial follicle development in the ovary. Ovaries from four-day old female rat pu...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-11133 | biostudies-arrayexpress
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