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TranscriptomicsmiRNA profile of microglial cells under oxygen-glucose deprivation
Migroglia cells were exposed to oxygen-glucose deprivation (OGD) for 3 h. The miRNA was isolated and the expression profiles of OGD-activated cells were compared with the profiles of resting cells. Two samples were analysed. miRNAs that were differentially expressed (increased or decreased in expres...
ORGANISM(S): Rattus norvegicus 
2015-11-23 | E-GEOD-63504 | biostudies-arrayexpress
TranscriptomicsTime resolved ribosome profiling study of oxygen and glucose deprivation of rat pheochromocytoma cells
Oxygen and glucose metabolism plays a pivotal role in many (patho)physiological conditions. In particular, oxygen and glucose deprivation (OGD) occurs during ischemia and stroke, resulting in extensive tissue injury and cell death. We applied time-resolved ribosome profiling technique to assess earl...
ORGANISM(S): Rattus norvegicus 
2015-04-10 | E-GEOD-60752 | biostudies-arrayexpress
TranscriptomicsLactic acidosis triggers starvation response with distinct metabolic profiles
[1] Lactic acidosis time course: MCF7 cells were exposed to lactic acidosis for different length of time. We used microarrays to examine the genomic programs of cells incubated under lactic acidosis for different length of time [2] Metabolic profiling: MCF7 cells were exposed to control condition, ...
ORGANISM(S): Homo sapiens 
2010-09-27 | E-GEOD-19123 | biostudies-arrayexpress
TranscriptomicsExpression analysis of the glucose deprivation-induced human tumor cell responses
The tumor microenvironment is characterized by low glucose and hypoxia. It is well known that changes in the tumor microenvironment, such as hypoxia and low glucose, can increase the production of VEGF. Although the role of hypoxia in the regulation of VEGF production is well understood, the mechani...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-38583 | biostudies-arrayexpress
GenomicsExpression data from human astrocytes (HA) under oxygen-glucose deprivation / reoxygenation
Expression data from human astrocytes (HA) under oxygen-glucose deprivation / reoxygenation
PRJNA699566 | ENA
GenomicsExpression profile of primary murine astrocyte-enriched cultures (AEC) exposed to oxygen-glucose deprivation
Expression profile of primary murine astrocyte-enriched cultures (AEC) exposed to oxygen-glucose deprivation
PRJNA931909 | ENA
TranscriptomicsGlobal transcriptomic profiling of oxygen-glucose deprivation (OGD)-mediated neuronal injury
Oxygen-glucose deprivation (OGD) is a cellular phenomenon consistently observed upon occurrence of ischemic stroke which eventually results in neuronal death. Neuronal cell death after ischemia takes place via two distinct processes, necrosis and apoptosis. Apoptosis, programmed cell death, is denot...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-23158 | biostudies-arrayexpress
GenomicsThe Atypical Antidepressant Tianeptine Confers Neuroprotection against Oxygen-Glucose Deprivation
The Atypical Antidepressant Tianeptine Confers Neuroprotection against Oxygen-Glucose Deprivation
PRJNA983251 | ENA
ProteomicsSUMO2/3 modification of transcription-associated proteins controls cell viability in response to oxygen and glucose deprivation-mediated stress
Because limited oxygen and glucose supply to tissues is a serious challenge that cells must properly measure to decide between surviving or triggering cell death, organisms have developed accurate mechanisms for sensing and signaling these conditions. In recent years, signaling through posttranslati...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD056069 | Pride
Sumoylation Ogd Hypoxia Senp7 Cell viability 
ProteomicsProteomic analysis identifies the potential effects of trichostatin A and bone marrow-derived dendritic cells on NIH3T3 cells under oxygen–glucose deprivation conditions
Fibroblasts usually mediate acute wound healing and long-term tissue remodeling with scarring in tissue injury. In myocardial infarction (MI), following a prolonged lack of oxygen supply, necrotized cardiomyocytes become replaced by secreted extracellular matrix proteins produced by fibroblasts. Den...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-21 | PXD021469 | Pride
Tsa  bmdcs  nih3t3 cells  fatty acid metabolism 
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