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ProteomicsIndoxyl sulfate and p-cresyl sulfate directly promote vascular calcification via activation of inflammation and coagulation pathways
Vascular calcification contributes to high cardiovascular mortality in chronic kidney disease (CKD) patients. An association between the uremic toxins indoxyl sulfate (IS) and p-cresyl sulfate (PCS) and cardiovascular disease has been suggested. This study provides strong etiological evidence for in...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-06-13 | PXD012582 | Pride
Indoxyl sulfate Chronic kidney disease Vascular calcification Inflammation Hyperglycemia Coagulation P-cresyl sulfate Itraq-8plex 
GenomicsTranscriptional profiling of human monocytes treated with indoxyl sulfate (IS) or p-cresyl sulfate (PCS)
Transcriptional profiling of human monocytes treated with indoxyl sulfate (IS) or p-cresyl sulfate (PCS)
PRJNA649416 | ENA
Unknownp-Cresyl sulfate and indoxyl sulfate in hemodialysis patients.
Not available
S-EPMC2798868 | biostudies-literature
UnknownRenal clearance and intestinal generation of p-cresyl sulfate and indoxyl sulfate in CKD.
Not available
S-EPMC3805062 | biostudies-literature
TranscriptomicsTranscriptional profiling of human monocytes treated with indoxyl sulfate (IS) or p-cresyl sulfate (PCS)
End-stage renal disease (ESRD) is the final stage of chronic kidney disease, which is increasingly prevalent worldwide and is associated with the progression of cardiovascular disease (CVD). Indoxyl sulfate (IS) and p-cresyl sulfate (PCS), major uremic toxins, are major risk factors involved in the ...
ORGANISM(S): Homo sapiens 
2020-07-30 | GSE155325 | GEO
UnknownThe uremic toxicity of indoxyl sulfate and p-cresyl sulfate: a systematic review.
Not available
S-EPMC4147984 | biostudies-literature
UnknownUnambiguous Characterization of p-Cresyl Sulfate, a Protein-Bound Uremic Toxin, as Biomarker of Heart and Kidney Disease.
Not available
S-EPMC6832250 | biostudies-literature
Unknownp-Cresyl sulfate promotes insulin resistance associated with CKD.
Not available
S-EPMC3537215 | biostudies-literature
UnknownIndoxyl Sulfate and p-Cresyl Sulfate Promote Vascular Calcification and Associate with Glucose Intolerance.
Not available
S-EPMC6493976 | biostudies-literature
UnknownThe relationship of indoxyl sulfate and p-cresyl sulfate with target cardiovascular proteins in hemodialysis patients.
Not available
S-EPMC7884394 | biostudies-literature
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