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Tomato fruit phenotypes are shaped by genotype, agronomic management and local environment, yet matched molecular and environmental datasets from commercial field settings remain scarce. Here we describe a paired resource comprising fruit transcriptomes, untargeted metabolomes, fruit-quality meas...

2026-09-14 | MTBLS15436 | MetaboLights
Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long span paired-end-tag (PET) sequencing approach using 10 Kb genomic DNA inserts to study human genome structural variations (SVs). The use of 10 Kb insert size allows the identification of brea...
ORGANISM(S): Homo sapiens 
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. Genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs. The current application of PET sequencing with...
ORGANISM(S): Homo sapiens 
Professional drivers represent an ideal cohort for investigating the effects of solar radiation on skin due to their unique, asymmetric exposure to sun, a consequence of vehicle window orientations. Consequently, one side of the face is naturally subjected to more solar radiation, resulting in uneve...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050746 | Pride
ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of proteinM-bM-^@M-^SDNA interactions in-vivo in the genome. In general, current algorithms for ChIP-seq reads employ artificial estimation ...
ORGANISM(S): Arabidopsis thaliana 
The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation requires formation of correct secondary structure through encoded base-pairing interacti...
ORGANISM(S): Arabidopsis thaliana 
Worldwide, breast cancer is the main cause of cancer mortality in women. Most cases originate in mammary ductal cells that secrete the nipple aspirate fluid (NAF). In cancer patients, this breast secretome contains proteins associated with the tumor microenvironment. NAF studies are challenging beca...
ORGANISM(S): Homo sapiens (Human) 
2019-04-23 | PXD005157 | Pride
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