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MetabolomicsA paired transcriptomic, metabolomic and fruit-quality data resource from field-grown tomatoes across eight agricultural sites in Ningxia, China

Tomato fruit phenotypes are shaped by genotype, agronomic management and local environment, yet matched molecular and environmental datasets from commercial field settings remain scarce. Here we describe a paired resource comprising fruit transcriptomes, untargeted metabolomes, fruit-quality meas...

2026-09-14 | MTBLS15436 | MetaboLights
GenomicsComprehensive Long Span Paired-End-Tag Mapping Reveals Characteristic Patterns of Structural Variations in Epithelial Cancer Genomes
Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long span paired-end-tag (PET) sequencing approach using 10 Kb genomic DNA inserts to study human genome structural variations (SVs). The use of 10 Kb insert size allows the identification of brea...
ORGANISM(S): Homo sapiens 
2011-04-06 | E-GEOD-26954 | biostudies-arrayexpress
MetabolomicsSeawater Analysis by Ambient Mass Spectrometry-Based Seaomics

A transmission mode-direct analysis in real time-quadrupole time of flight-mass spectrometry (TM-DART-QTOF-MS)-based analytical method coupled to multivariate statistical analysis was developed to interrogate lipophilic compounds in seawater samples without the need of desalin...

2020-05-19 | MTBLS1198 | MetaboLights
GenomicsLong Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. Genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs. The current application of PET sequencing with...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-32674 | biostudies-arrayexpress
ProteomicsPaired Proteomic Analysis of Sun-Exposed Skin of Professional Drivers Reveals altered abundance of Keratins, S100A14, Hemoglobin, and F-box Proteins.
Professional drivers represent an ideal cohort for investigating the effects of solar radiation on skin due to their unique, asymmetric exposure to sun, a consequence of vehicle window orientations. Consequently, one side of the face is naturally subjected to more solar radiation, resulting in uneve...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050746 | Pride
Photoaging  proteomics  paired  skin  sun-exposed 
ProteomicsDifferential proteomic comparison of the breast cancer secretome using a quantitative paired analysis workflow
Worldwide, breast cancer is the main cause of cancer mortality in women. Most cases originate in mammary ductal cells that secrete the nipple aspirate fluid (NAF). In cancer patients, this breast secretome contains proteins associated with the tumor microenvironment. NAF studies are challenging beca...
ORGANISM(S): Homo sapiens (Human) 
2019-04-23 | PXD005157 | Pride
Paired analysis Breast cancer Tumor microenvironment 
TranscriptomicsGenome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis
The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation requires formation of correct secondary structure through encoded base-pairing interacti...
ORGANISM(S): Arabidopsis thaliana 
2010-10-04 | E-GEOD-23439 | biostudies-arrayexpress
MetabolomicsMulti-omics Analysis of ACAD11-mediated Lipid Metabolic Reprogramming in the Prognosis of Clear Cell Renal Cell
Clear cell renal cell carcinoma (ccRCC) is pathologically characterized by profound intracellular lipid droplet accumulation. To explore the dysregulated lipid metabolic network and identify crucial drivers, an integrated transcriptomic and untargeted metabolomic analysis was conducted. In this stud...
2026-08-31 | MTBLS15414 | MetaboLights
GenomicsAn effective approach for identification of in vivo proteinM-bM-^@M-^SDNA binding sites from paired-end ChIP-Seq data
ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of proteinM-bM-^@M-^SDNA interactions in-vivo in the genome. In general, current algorithms for ChIP-seq reads employ artificial estimation ...
ORGANISM(S): Arabidopsis thaliana 
2010-06-04 | E-GEOD-16940 | biostudies-arrayexpress
MetabolomicsFinger sweat analysis enables short interval metabolic biomonitoring in humans

Metabolic biomonitoring in humans is typically based on the sampling of blood, plasma or urine. Although established in the clinical routine, these sampling procedures are often associated with a variety of compliance issues and are impractical for performing time-course studies. The analysis of ...

2021-08-13 | MTBLS2776 | MetaboLights
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