Pancreatic cancer (pc)

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Unknown (1462)
Transcriptomics (382)
Genomics (116)
Proteomics (29)
Metabolomics (5)
Clinical (4)
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Other (2)
Models (1)

Organisms

Homo sapiens (292)
Mus musculus (90)
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Drosophila melanogaster (3)
Bradyrhizobium diazoefficiens USDA 110 (2)
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Emiliania huxleyi (2)
Rattus (1)
Metallosphaera sedula DSM 5348 (1)
Osmerus mordax (1)
Oncorhynchus nerka (1)
Tetrahymena thermophila (1)
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Streptococcus mutans (1)
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mouse gut metagenome (1)
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Caenorhabditis elegans (1)
Plasmodium falciparum (1)
Canis lupus familiaris (1)

Organisms

Homo sapiens (40)
Mus musculus (12)
human oral metagenome (1)

Repository

biostudies-arrayexpress (380)
ENA (76)
geo (43)
pride (14)
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ExpressionAtlas (1)
BioModels (1)
EVA (1)
GNPS (1)

Tissue

Pancreas (4)
Cell culture (3)
Cyst fluid (2)
Blood plasma (2)
Blood serum (2)
Epithelial cell (2)
Fibroblast (1)
Pancreatic cancer cell (1)
Pancreatic cancer cell line (1)
Permanent cell line cell (1)

Disease

Glioblastoma (2)
Melanoma (2)
AIDs related Burkitts lymphoma (1)
Acute lymphoblastic (T-ALL) leukemia (1)
Acute lymphoblastic leukemia (1)
Adenocarcinoma HER2/ERBB2 transfectant of MDA-MB-435 melanoma (1)
Adenocarcinoma of colon (1)
Adenocarcinoma of lung (1)
Adenocarcinoma of prostate (1)
Adenocarcinoma prostate PC-3 subline isolated from liver metastasis in mice (1)
Adenocarcinoma, breast grown from mouse mammary fat pad (1)
Anaplastic astrocytoma (1)
Breast adenocarcinoma (1)
Carcinoma, renal cell (1)
Cervical adenocarcinoma (1)
Chronic myelogenous (blast crisis) leukemia (1)
Colon carcinoma (1)
Gastric adenocarcinoma (1)
Hepatocellular carcinoma (1)
Large cell lung carcinoma (1)
Large cell undifferentiated lung (1)
Lymphoblastic Burkitt's lymphoma (1)
Malignant amelanocytic melanoma (1)
Malignant melanoma (1)
Metastatic malignant melanoma (1)
Non-small cell lung carcinoma (1)
Ovarian adenocarcinoma (1)
Ovarian carcinoma (1)
Pancreatic adenocarcinoma (1)
Poorly differentiated B cell origin leukemia (1)

Technology Type

Mass Spectrometry (16)
Shotgun proteomics (6)
Mass spectrometry (2)
ESI (2)
Bottom-up proteomics (2)
Top-down proteomics (2)
Affinity purification coupled with mass spectrometry proteomics (1)
All-ion fragmentation (1)
Data-dependent acquisition (1)
Data-independent acquisition (1)
Gel-based experiment (1)
HDMSE (1)

Instrument Platform

NextSeq 500 (10)
Illumina NovaSeq 6000 (7)
Illumina HiSeq 2500 (4)
Illumina HiSeq 2000 (4)
Agilent G2565AA and G2565BA Microarray Scanner (2)
Chemostat (2)
Axon- GenePix4000B (2)
GenePix 4000B [Axon Instruments] (2)
FACS Aria-III (2)
Illumina NovaSeq X (2)
NextSeq 2000 (2)
Illumina MiSeq (2)
Illumina HiSeq 4000 (2)
Whole Transcriptome v2 kit (1)
10x Chromium v3 (1)
PromethION (1)
G2565BA DNA microarray scanner (1)
ArrayWoRx Multi-Format Reader [Applied Precision] (1)
Affymetrix GeneArray Scanner (1)
Affymetrix GeneChip Scanner 3000 (GCS3000) (1)
Typhoon TRIO (1)
ScanArray 4000 [PerkinElmer] (1)
GeneChip Scanner 3000 7G (1)
GenePix Professional 4200A [Axon Instruments] (1)
G2565AA DNA microarray scanner [Agilent] (1)
G2505A DNA microarray scanner [Agilent] (1)
G2565BA DNA microarray scanner [Agilent] (1)
Scanning hardware (1)
Affymetrix Fluidics Station 400 (1)
Racham server on Uppmax, NAISS (1)

Publication Date

2013 (50)
2010 (43)
2012 (40)
2014 (37)
2011 (35)
2015 (28)
2016 (27)
2005 (24)
2025 (23)
2008 (18)
2009 (17)
2022 (14)
2026 (13)
2023 (11)
2021 (11)
2017 (11)
2006 (11)
2024 (10)
2007 (9)
2018 (8)
2020 (7)
2019 (5)
2004 (2)

ENSEMBL ID

ENSG00000115415 (1)
ENSG00000185338 (1)

CHEBI ID

CHEBI:15428 (1)
CHEBI:42111 (1)

Metabolite Name

Adenosine_ peak 2 (1)
Alpha-Solanine_ in-source fragment (1)
Alpha-Solanine_ in-source fragment _- Fucose_ (1)
Alpha-Solanine_ in-source fragment _- Hexose_ (1)
Biochanin A_ internal standard (1)
Citric acid (1)
Feruloyl agmatine trans (1)
Glycine (1)
IAA-valine_ IAA-Val_ Indole-3-acetyl-valine (1)
Kaempferol IS fragment 287.055 RT 4.20 (1)
Kinetin (1)
L-Leucine (1)
L-Phenylalanine (1)
L-Tyrosine_ peak 2_ -NH2 (1)
Rhapontin_ Rhaponticin_ Ponticin_ Rhaponiticin_ 4_-Methoxy-3_3__5-stilbenetriol-3-glucoside_ in-source fragment -glc (1)
Riboflavin_ Vitamin B2 (1)
Rutin _Quercetin _ Hex _ Fuc_ RT 4.61 m_z 611.159 (1)
Scoparone_ 6_7 Dimethoxycoumarin_ 6_7-Dimethylesculetin (1)
Solanine (1)
Solanine IS fragment m_z 560.393 (1)
Trigonelline_ N-Methylnicotinate (1)
Tryptamine _-NH2_ (1)
Tryptophan (1)
Tyramine_ in-source fragment _-NH2__ peak 1 (1)
Tyrosine (1)

First Public Date

2026 (12)
2022 (11)
2024 (10)
2023 (10)
2014 (7)
2025 (6)
2021 (5)
2020 (4)
2019 (3)
2016 (3)
2018 (2)
2017 (1)
2015 (1)
2013 (1)

Modelling Approach

Ordinary differential equation model (1)

Study status

Completed (2)
Recruiting (1)
Withdrawn (1)

Lab affiliation

1. Garvan Institute of Medical Research, Cancer Ecosystems Program, and The Kinghorn Cancer Centre, Darlinghurst, Sydney, New South Wales, Australia. 2. School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales (UNSW), Kensington, Sydney, New South Wales, Australia. (1)
1INSERM, U1068, Cancer Research Center of Marseille, Institut Paoli-Calmettes, CNRS, UMR7258, and University Aix-Marseille, Marseille, France (1)
A2 Biotherapeutics (1)
Assistant Professor Department of Pathology University of South Alabama Mobile, Alabama United States (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) School of Life Sciences Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY Bavarian Center for Biomolecular Mass Spectrometry Technische Universität München Gregor-Mendel-Straße 4 85354 Freising DEUTSCHLAND / GERMANY (1)
Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK (1)
Department of Laboratory Medicine and Pathology, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA (1)
Department of Oncology, Shengjing Hospital of China Medical University,Shenyang, People's Republic of China (1)
Helmholtz Pioneer Campus, Helmholtz Zentrum München, Munich, Germany and Medical Faculty, Technical University of Munich, Munich, Germany (1)
Mass Spectrometry and Proteomics Facility, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3052, Australia (1)
Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan. (1)
Professor in Translational Oncology Director of Postgraduate Teaching and Learning, School of Medicine Principal Investigator, Cancer Chemoradiation Research Group Department of Surgery, Trinity Translational Medicine Institute Trinity College Dublin, St. James’s Hospital, Dublin (1)
Professor in Translational Oncology Director of Postgraduate Teaching and Learning, School of Medicine Principal Investigator, Cancer Chemoradiation Research Group Department of Surgery, Trinity Translational Medicine Institute, Trinity St. James’s Cancer Institute, Rm 1.20, Trinity Centre for Health Sciences, Trinity College Dublin, St. James’s Hospital, Dublin 8, D08 W9RT, Ireland. (1)
Transplantation Laboratory, Haartman Institute, University of Helsinki, Finland (1)

Keyword

Capecitabine (1)
EGF ointment (1)
EGFR inhibitor (1)
Neurotoxicity (1)
Oxaliplatin based chemotherapy (1)
Skin side effect (1)

IsPrivate

False (1)

Study type

Transcription profiling by array (240)
RNA-seq of coding RNA (29)
ChIP-seq (22)
ChIP-chip by tiling array (13)
RNA-seq of coding RNA from single cells (12)
ChIP-chip by array (9)
Comparative genomic hybridization by array (9)
Methylation profiling by array (9)
Unknown experiment type (5)
Methylation profiling by high throughput sequencing (5)
RNA-seq of non coding RNA (5)
Other (4)
Interventional (4)
MicroRNA profiling by array (3)
Genotyping by array (2)
Transcription profiling by RT-PCR (2)
RNA-seq of non coding RNA from single cells (1)
Differential (1)
Cell line - One-color microarray (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
MicroRNA profiling by high throughput sequencing (1)
DNA-seq (1)
CUT&RUN (1)
RNA-seq of total RNA (1)

Release Date

2022 (223)
2023 (212)
2025 (183)
2021 (180)
2024 (151)
2020 (143)
2018 (86)
2016 (82)
2019 (78)
2017 (65)
2013 (65)
2015 (63)
2014 (52)
2010 (49)
2012 (46)
2011 (42)
2026 (34)
2005 (24)
2009 (21)
2008 (19)
2006 (12)
2007 (10)
2004 (2)

Location

Belgium (1)
France (1)
South Korea (1)
Spain (1)
United States (1)

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Chronic pancreatitis vs pancreatic cancer LC-MS

Age-standardized incidence rates for pancreatic cancer (PC) in men have increased by 25% from 1957 to 2011 in Finland. The average age of diagnosis for PC is 69 years in Nordic males, whereas the average age of diagnosis of chronic pancreatitis (CP) is 40-50 years, but the cases overlap in age. By r...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2018-08-31 | MSV000082883 | MassIVE

Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights

CD9, a key mediator of pancreatic cancer cell aggressiveness driven by CAFs-derived extracellular vesicles

While of growing interest in pancreatic cancer (PC) field, the stromal-tumor cells crosstalk lags behind in terms of biomarkers and therapeutic options improving the clinical armamentarium. Knowledge on cellular communications was drastically enhanced following the discovery of extracellular vesicle...

ORGANISM(S): Homo sapiens (Human)

2022-08-21 | PXD023165 | Pride

Extracellular vesicles from pancreatic cancer cells activate mast cells which in turn promote tumor cell proliferation and establish a tumor-supportive microenvironment

Background and aim: Recent studies reveal a critical role of tumor cell-released extracellular vesicles (EVs) in pancreatic cancer progression. Driver genes directing EV function, the EV-recipient cells, as well as their cellular response to EV uptake remain, however, to be identified. To address th...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2023-12-06 | MSV000093583 | MassIVE

LC-MS/MS analysis of pancreatic cancer plasma

Pancreatic cancer (PC) is an aggressive cancer with a high mortality rate, necessitating the de-velopment of effective diagnostic, prognostic and predictive biomarkers for disease manage-ment. Aberrantly fucosylated proteins in PC are considered a valuable resource of clinically useful biomarkers. T...

ORGANISM(S): Homo sapiens (Human)

2021-09-10 | PXD025150 | Pride

Itraq-based quantitative proteome Pancreatic cancer Aal Fucosylated serpina1 Plasma Glycobiomarker Reverse lectin-based elisa

Pancreatic Cancer HPAF/CD18 cells: Ecd knockdown vs Scrambled

Purpose: To study the expression and function of a novel cell cycle regulatory protein, human ecdysoneless (Ecd), during pancreatic cancer (PC) pathogenesis. Experimental Design: Immunohistochemical expression profiling of Ecd was done in non-neoplastic normal pancreatic tissues and pancreatic ducta...

ORGANISM(S): Homo sapiens

2012-08-09 | E-GEOD-39988 | biostudies-arrayexpress

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133B]

Pancreatic cancer is a devastating disease with both local invasion and distant metastasis. Identifying the genes expressed in liver metastases and signatures of metastatic progression would therefore be of particular importance as they could aid in both recurrence prediction as well as representing...

ORGANISM(S): Homo sapiens

2013-08-15 | E-GEOD-19280 | biostudies-arrayexpress

Induction of apoptotic processes in Capan-1 pancreatic carcinoma cells by restoration of p16INK4a expression

Early invasive growth and metastasis are features of pancreatic cancer that rely on resistance to anoikis, an apoptosis program activated upon loss of adequate matrix anchorage. Re-expression of the tumor suppressor p16 reversed anoikis resistance of pancreatic cancer cells. This conversion to an an...

ORGANISM(S): Homo sapiens

2010-08-01 | E-GEOD-22334 | biostudies-arrayexpress

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133A]

ORGANISM(S): Homo sapiens

2013-08-15 | E-GEOD-19279 | biostudies-arrayexpress

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133_Plus_2]

We and others have shown that S100P is highly upregulated during the progression of pancreatic cancer. We used microarrays to look at the target genes regulated by S100P in the pancreatic cancer cell line Panc1. Keywords: Gene overexpression We generated stable cell lines by introducing control vec...

ORGANISM(S): Homo sapiens

2013-08-15 | E-GEOD-19278 | biostudies-arrayexpress

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