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TranscriptomicsH2-ab1 Mouse Parent of Origin
We looked for parent of origin effects on genome-wide gene expression in a reciprocal cross between C57BL/6J x B6(C)-H2bm12/KhEgJ mice (the latter strain is a knockout of H2-ab1 on a C57BL/6J background). The aim is to find genes whose expression is altered in trans depending on whether the mother o...
ORGANISM(S): Mus musculus 
2013-11-01 | E-MTAB-1998 | biostudies-arrayexpress
TranscriptomicsTenascin-C modifies expression levels and territories of key patterning genes during spinal cord astrocyte specification [mus musculus]
We demonstrate for the first time that the extracellular matrix glycoprotein Tenascin-C regulates the expression of key patterning genes during late embryonic spinal cord development, leading to a timely maturation of gliogenic neural precursor cells. We first show that Tenascin-C is expressed by gl...
ORGANISM(S): Mus musculus 
2011-10-19 | E-GEOD-33091 | biostudies-arrayexpress
GenomicsAnalysis of Hybrid Incompatability between C nigoni and C briggsae
Analysis of Hybrid Incompatability between C nigoni and C briggsae
PRJNA305287 | ENA
ProteomicsCarboxypeptidase B-assisted charge-based fractional diagonal chromatography for deep screening of C-terminome
The determination of protein C-termini is of great significance for protein function annotation and proteolysis re-search. However, the progress of C-terminomics is still far behind its counterpart, N-terminomics, because of the low reactivity of the carboxyl group. Herein, we developed a negative s...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2020-05-25 | PXD018520 | Pride
Chafradic Cleavage site C-terminomic Caspase 
GenomicsAnalysis of Hybrid Incompatability between C nigoni and C briggsae by mRNA sequencing
Analysis of Hybrid Incompatability between C nigoni and C briggsae by mRNA sequencing
PRJNA306868 | ENA
TranscriptomicsStaphylococcus aureus walKR mutants (TPS3130 and TPS3190) vs. parent strains (JKD6009 and JKD6004)
WalKR is an essential two component regulatory system in S. aureus, thought to control cell wall metabolism. Using genome sequencing of 5 paired clinical isolates of vancomycin-susceptible and vancomycin-intermediate S. aureus we found frequent, but unique, mutations in this locus. To investigate th...
ORGANISM(S): Staphylococcus aureus 
2012-05-31 | E-GEOD-29157 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of two highly Ara-C resistant cell lines, B117H and B140H and two Ara-C sensitive parental cell lines, B117P and B140P to study altered gene expression in acute myeloid leukemia cell lines.
A microarray study of altered gene expression in acute myeloid leukemia cell lines Experiment Overall Design: Two highly Ara-C resistant cell lines, B117H and B140H were derived from Ara-C sensitive parental cell lines, B117P and B140P. Variations in gene expression between these resistant/sensitiv...
ORGANISM(S): Mus musculus 
2007-12-01 | E-GEOD-2788 | biostudies-arrayexpress
TranscriptomicsRNA-seq of hvsnac1.e (E) and Sebastian parent variety (S) during control (C) and drought stress (D)
Drought stress can damage crop growth and lead to a decline in yield, thereby affecting food security, especially in regions vulnerable to climate change. SNAC1 (Stress-responsive NAC1), the NAC transcription factor family member, plays a crucial role in stomatal movement regulation. Effective regul...
ORGANISM(S): Hordeum vulgare subsp. vulgare 
2025-02-12 | E-MTAB-14769 | biostudies-arrayexpress
GenomicsAnalysis of Hybrid Incompatability between C nigoni and C briggsae
An introgression of C. briggsae onto the X chromosome of C briggsae results in male sterility. In order to determine the cause, we sequenced small RNAs from this strain and compared to fertile males of the two parent species.
ORGANISM(S): Caenorhabditis briggsae Caenorhabditis nigoni 
2016-05-11 | GSE75763 | GEO
TranscriptomicsNiemann-Pick type C fibroblast analysis
Primary skin fibroblasts from four Niemann-Pick type C patients homozygous for the I1061T mutation and four control individuals were cultured under identical conditions in DMEM containing 10% fetal bovine serum. Cells were harvested at 50-70% confluency. mRNA was isolated with the FastTrack 2....
ORGANISM(S): Homo sapiens 
2007-08-15 | E-GEOD-8770 | biostudies-arrayexpress
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