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We conducted comparative proteomic analysis with clear cell renal cell carcinoma (ccRCC), a subtype of RCC, have poorer prognosis and metastasize to the lungs, bones and lymph nodes. Comparative proteomic analysis in ccRCC study will reveals novel insights and development of disease.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045898 | Pride
Prostate cancer (PCa) is one of the most common cancers diagnosed in men in the world. The majority of patients develop resistant to androgen deprovation therapy, leading to castration-resistant PCa (CRPC). CRPC have a poorer prognosis and developing metastasis compared to hormone-sensitive PCa. To ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD056553 | Pride
: Prostate cancer (PCa) is the most commonly diagnosed genital cancer in men worldwide. Among patients who developed advanced PCa, 80% suffered from bone metastasis, with a sharp drop in the survival rate. Using quantitative global succinylome analysis, we characterized a significant increase of ly...
ORGANISM(S): Homo sapiens (Human) 
2023-06-21 | PXD022005 | Pride
During senescence of detached rice leaves, tryptophan (Trp) and Trp-derived secondary metabolites such as serotonin and 4-coumaroylserotonin accumulated in concert with methanol (MeOH) production. This senescence-induced MeOH induction was closely associated with levels of pectin methylesterase (PME...
ORGANISM(S): Oryza sativa 
Renal cell carcinoma (RCC) is among the top 8 most diagnosed cancer in United States, which 79,000 patients newly were diagnosed and 13,920 deaths [1]. The clear-cell RCC (ccRCC) is the most common histopathological subtype representing approximately 85~90% in all diagnosed case [2]. In renal cancer...
ORGANISM(S): Homo sapiens (Human) 
2024-01-30 | PXD039207 | Pride
Over 90% of kidney malignancies are renal cell carcinomas (RCC), which are tumors arising from the renal epithelium. Clear cell RCC (ccRCC) is the most frequent histological subtype and the cause of the majority of kidney cancer-related fatalities. Because of its low 5-year survival rate, poor progn...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039204 | Pride
To confirm the anti-metastatic effect in bladder cancer cell lines, the PDK4 gene was knocked down and phosphorylated protein changes were compared through LC-MS/MS analysis.
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD035005 | Pride
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