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ProteomicsNaive and DSS Murine Colon TMTpro bRP fractionation N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060852 | Pride
Mouse Protease Fractionation Legumain N-terminomics Colon Colitis 
ProteomicsMurine colon HUNTER N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060854 | Pride
Legumain Mouse Colon Colitis Hunter 
ProteomicsN-terminomics profiling of naive and inflamed murine colon reveals proteolytic signals of legumain
Legumain is a cysteine protease broadly associated with inflammation. It has recently been reported to cleave and activate protease-activated receptor 2 to provoke pain associated with oral cancer. Outside of gastric and colon cancer, little has been reported on the roles of legumain within the gast...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD051470 | Pride
Protease N-terminomics Legumain Colon Colitis 
UnknownAn NK-like CAR T cell transition in CAR T cell dysfunction.
Not available
S-EPMC8827167 | biostudies-literature
UnknownDetection of copy number variation by SNP-allelotyping.
Not available
S-EPMC4254366 | biostudies-literature
UnknownImplementation of a Multihospital Electronic Medical Record-Based Insulin Order Set to Reduce Hypoglycemic Events.
Not available
S-EPMC12744792 | biostudies-literature
TranscriptomicsTranscription profiling of human stage 1,2 normal and tumor kidney cancer
Although renal cell carcinoma (RCC) is the sixth-leading cause of cancer death, the molecular events leading to disease onset and progression are not well understood. Genomic profiling of clear cell RCC (cRCC) patients indicated that loss of a negative regulator of the Wnt pathway, secreted frizzled...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6344 | biostudies-arrayexpress
UnknownTraining Health Care Practitioners to Effectively Communicate With Older Adults With Cancer and Their Caregivers.
Not available
S-EPMC12453593 | biostudies-literature
UnknownEngineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class.
Not available
S-EPMC9481017 | biostudies-literature
UnknownAssociation of N-Terminal Pro-Brain Natriuretic Peptide Concentration in Early Pregnancy With Development of Hypertensive Disorders of Pregnancy and Future Hypertension.
Not available
S-EPMC8771430 | biostudies-literature
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