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TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alt...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-36933 | biostudies-arrayexpress
ProteomicsElongator is required for pattern recognition receptor and type I interferon signaling in macrophages.
Innate immune detection of pathogens by macrophages requires a rapid and large scale mobilisation of cellular resources towards an appropriate immune response, mainly involving altered protein expression. Pathogen recognition is mediated by pattern recognition receptor (PRR) sensing of conserved mic...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-22 | PXD064630 | Pride
Innate immunity  interferon  interferon regulatory factor (irf)  lipopolysaccharide (lps)  macrophage  pattern recognition receptor (prr)  stat transcription factor  toll-like receptor 4 (tlr4)  virus  elongator 
TranscriptomicsEffect of Drosophila immune proteins on gene expression in E. coli
Interaction between the host and invading pathogen determines the fate of both organisms during the infectious state. The host is equipped with a battery of immune reactions, while the pathogen displays a variety of mechanisms to compromise host immunity. Although bacteria alter their pattern of g...
ORGANISM(S): Escherichia coli 
2015-01-13 | E-GEOD-61604 | biostudies-arrayexpress
ProteomicsGenotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1
Pattern-triggered immunity (PTI) is a central component of plant immunity. Activation of PTI relies on the recognition of microbe-derived structures, termed patterns, through plant encoded surface-resident pattern recognition receptors (PRRs). We have identified proteobacterial translation initiatio...
ORGANISM(S): Escherichia coli 
2022-03-03 | PXD031124 | Pride
Pattern recognition receptor Proteobacterial protein translation initiation factor 1 Plant immunity 
GenomicsCancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition
Cancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition
PRJNA1298211 | ENA
TranscriptomicsRNA sequencing reveals novel gene clusters in bovine conceptuses associated with maternal recognition of pregnancy and implantation
Successful establishment and maintenance of pregnancy can be attained only through optimum conceptus-maternal cross talk. Despite significant progress in our understanding of the temporal changes in the transcriptome of the uterine endometrium, we have only a rudimentary knowledge of the genes and p...
ORGANISM(S): Bos taurus 
2014-04-04 | E-GEOD-56513 | biostudies-arrayexpress
GenomicsBacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
Bacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
PRJNA835140 | ENA
ProteomicsPeptidoglycan metabolite photoaffinity reporters reveal direct binding to intracellular pattern recognition receptors and Arf GTPases
Extensive structure-activity studies of iE-DAP and MDP have demonstrated their selective activation of NOD1- and NOD2-expressing cells, respectively. Nonetheless, the direct binding of iE-DAP and MDP to NOD1 and NOD2, respectively, as well as other proteins in mammalian cells has not been systematic...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012350 | Pride
Mdp Gel-based proteomics Nod2 Hek293t 
TranscriptomicsGene expression study reveals compromised Pattern Recognition Receptors and Interferon Signaling in fullterm Low birth Weight newborns
Low Birth Weight (LBW) newborns (with weight less than 2500g) suffer a higher frequency and severity of microbial infection than normal birth weight (NBW) newborns. Morbidity and mortality of LBW infants due to infectious diseases are known to be high and it has been associated with compromised immu...
ORGANISM(S): Homo sapiens 
2012-01-15 | E-GEOD-29807 | biostudies-arrayexpress
UnknownA continuous linear optimal transport approach for pattern analysis in image datasets.
Not available
S-EPMC4742369 | biostudies-literature
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