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TranscriptomicsTranscription profiling of human peripheral blood monocytes in periodontal therapy
Periodontal infections have been associated with systemic inflammation and risk for atherosclerosis and vascular disease. We investigated the effects of comprehensive periodontal therapy on gene expression of peripheral blood monocytes. Approximately 1/3 of the patients showed substantial changes in...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6751 | biostudies-arrayexpress
TranscriptomicsTranscriptomes in Healthy and Diseased Gingival Tissues
We examined gene expression signatures in healthy and diseased gingival tissues in 90 patients. Analysis of the gingival tissue transcriptome in states of periodontal health and disease may reveal novel insights of the pathobiology of periodontitis. Keywords: gingival tissue disease state analysis N...
ORGANISM(S): Homo sapiens 
2008-12-22 | E-GEOD-10334 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gingival tissue from patients with periodontitis: Bacterial Correlates of Gingival Gene Expression
We investigated the association between subgingival bacterial profiles and gene expression patterns in gingival tissues of patients with periodontitis. A total of 120 patients undergoing periodontal surgery contributed with a minimum of two interproximal gingival papillae (range 2-4) from a maxillar...
ORGANISM(S): Homo sapiens 
2009-12-21 | E-GEOD-16134 | biostudies-arrayexpress
TranscriptomicsStriatum of Huntington's disease model mice [Affymetrix data]
Evaluation of transcriptional changes in the striatum may be an effective approach to understanding the natural history of changes in expression contributing to the pathogenesis of Huntington disease (HD). We have performed genome-wide expression profiling of the YAC128 transgenic mouse model of HD ...
ORGANISM(S): Mus musculus 
2010-02-21 | E-GEOD-18551 | biostudies-arrayexpress
UnknownEvaluation of connectivity map shows limited reproducibility in drug repositioning.
Not available
S-EPMC8413422 | biostudies-literature
UnknownMetaanalysis of flawed expression profiling data leading to erroneous Parkinson's biomarker identification.
Not available
S-EPMC4507209 | biostudies-literature
UnknownProtease-Inhibitor Interaction Predictions: Lessons on the Complexity of Protein-Protein Interactions.
Not available
S-EPMC5461536 | biostudies-literature
UnknownBias tradeoffs in the creation and analysis of protein-protein interaction networks.
Not available
S-EPMC3972268 | biostudies-literature
UnknownCharacterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets.
Not available
S-EPMC10317128 | biostudies-literature
UnknownCataloging the potential functional diversity of Cacna1e splice variants using long-read sequencing.
Not available
S-EPMC12465193 | biostudies-literature
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