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TranscriptomicsAntenatal Blood DNA Methylation Profiles
DNA methylation profiles were generating using Illumina HM450 microarrays in a prospective sample blood from the prenatal period of pregnant mood disorder patients who would and would not develop depression post partum. We recruited 54 pregnant women with a history of either Major Depression or Bipo...
ORGANISM(S): Homo sapiens 
2013-05-24 | E-GEOD-44132 | biostudies-arrayexpress
UnknownThe architecture of an empirical genotype-phenotype map.
Not available
S-EPMC6055911 | biostudies-literature
TranscriptomicsEstrogen Induced DNA Methylation Changes in Mouse Hippocampus
Estrogen, specifically estradiol, has been shown to mediate DNA methylation changes at mutiple locations downstream of estrogen response elements (EREs). We identified differentially methylated regions associated with long-term estradiol exposure in the hippocampus of C57BL/6J mice. Hippocampus was ...
ORGANISM(S): Mus musculus 
2013-05-24 | E-GEOD-43460 | biostudies-arrayexpress
MetabolomicsThe genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides

Cyclic peptides are reported to have antibacterial, antifungal and other bioactivities. Orbitides are a class of cyclic peptide that are small, head-to-tail cyclized, composed of proteinogenic amino acids, and lack disulfide bonds; they are also known in several genera of the plant family Rutacea...

2020-10-14 | MTBLS1963 | MetaboLights
UnknownLower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity.
Not available
S-EPMC10666001 | biostudies-literature
UnknownPosition-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin.
Not available
S-EPMC10784704 | biostudies-literature
ProteomicsPosition-specific N- and O-glycosylation of the reactive centre loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin
Corticosteroid-binding globulin (CBG) delivers anti-inflammatory cortisol to inflamed tissues through the proteolytic cleavage of an exposed reactive centre loop (RCL) by neutrophil elastase (NE). We previously demonstrated that RCL-localised Asn347-linked N-glycans impact NE proteolysis, but a comp...
ORGANISM(S): Homo sapiens (Human) 
2023-12-05 | PXD046405 | Pride
Glycosylation O-glycosylation Corticosteroid-binding globulin Cortisol N-glycosylation Proteolysis Reactive centre loop Neutrophil elastase 
UnknownMethods to identify and prioritize patient-centered outcomes for use in comparative effectiveness research.
Not available
S-EPMC6047482 | biostudies-literature
UnknownGRACILE syndrome, a lethal metabolic disorder with iron overload, is caused by a point mutation in BCS1L.
Not available
S-EPMC378542 | biostudies-literature
UnknownE4206: AMG 706 and Octreotide in Patients with Low-Grade Neuroendocrine Tumors.
Not available
S-EPMC6192662 | biostudies-literature
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