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TranscriptomicsmiRNA array analysis following gefinitib/luteolin administration to PC-3 cells
To determine if any altered miRNA expression is actually involved in the growth inhibition and/or cell death induction by luteolin and/or gefitinib, we performed miR-array analysis using RNA from PC-3 cells after 24h of treatment with 60μM luteolin and/or 60μM gefitinib. PC-3 cells were treated fo...
ORGANISM(S): Homo sapiens 
2014-06-29 | E-GEOD-53178 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of orthoptic PC-3/FGF-8b- and PC-3/mock-transfected prostate tumors in nude mice
Our aim was to study the effect of FGF-8 on prostate tumor growth and to identify FGF-8b-associated molecular targets in the orthotopic PC-3 nude mouse model of prostate cancer.
ORGANISM(S): Mus musculus 
2008-03-04 | E-MEXP-1081 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis following gefinitib/luteolin administration to PC-3 cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-06-30 | E-GEOD-53181 | biostudies-arrayexpress
TranscriptomicsGenome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA
To determine the global effects of ASCT2 inhibition, we used next generation sequencing to determine mRNA expression changes in PC-3 cells treated with BenSer or GPNA for 48 h. Examination of two different ASCT2 inhibitors BenSer and GPNA in prostate cancer cell line PC-3.
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-65112 | biostudies-arrayexpress
GenomicsTrichoderma reesei strain:PC-3-7
Trichoderma reesei PC-3-7 Resequencing
PRJNA346780 | ENA
TranscriptomicsRD effect on PC-3 cells
RD induced DNA damage and suppressed DNA repair in PC-3 cells. Expression profiling of PC-3 cells treated with 10 umol/L RD for 24 hours. Total RNA was extracted from PC-3 cells exposed to RD for 24 h using an RNAiso plus kit (TaKaRa). Microarray analysis was performed on separate samples on the Aff...
ORGANISM(S): Homo sapiens 
2012-05-07 | E-GEOD-37812 | biostudies-arrayexpress
TranscriptomicsPC-3 cells: siControl vs. siRNA ARHGAP21
Transcriptional profiling of the prostate adenocarcinoma cell line PC-3 comparing control cells transfected with a pool of oligonucleotides control (siControl) with cells transfected a pool of oligonucleotides specific to inhibit ARHGAP21 expression (siARHGAP21). The efficiency of the transfection w...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-37888 | biostudies-arrayexpress
ProteomicsPCa_Secretome_PC3vsPC3nKR - Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells
Prostate cancer (PCa) is the most common cancer in American men. The American Cancer Society’s estimates for prostate cancer in the United States for 2017 are estimated 161.360 new cases and 26,730 deaths from PCa. To study metastatic properties to bone, PC-3 cell line is mainly used classical human...
ORGANISM(S): Homo sapiens (Human) 
2019-08-19 | PXD008184 | Pride
Pc-3 Pc-3/nkr Tmt labeling Prostate cancer 
TranscriptomicsGenome-wide analysis of androgen receptor (AR) SUMOylation effects on gene expression (PC-3).
Androgen receptor (AR) plays an important regulatory role during prostate cancer development. ARM-bM-^@M-^Ys transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications. To study the role of the AR SUMOylation in genuine chromatin environment, we compare...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54104 | biostudies-arrayexpress
GenomicsGenome-wide analysis of SUMOylation effects on androgen receptor (AR) binding in PC-3 cells (ChIP-seq)
Androgen receptor (AR) plays an important regulatory role during prostate cancer development. ARM-bM-^@M-^Ys transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications. To study the role of the AR SUMOylation in genuine chromatin environment, we compare...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54110 | biostudies-arrayexpress
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