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ProteomicsPCa_Secretome_PC3vsPC3nKR - Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells
Prostate cancer (PCa) is the most common cancer in American men. The American Cancer Society’s estimates for prostate cancer in the United States for 2017 are estimated 161.360 new cases and 26,730 deaths from PCa. To study metastatic properties to bone, PC-3 cell line is mainly used classical human...
ORGANISM(S): Homo sapiens (Human) 
2019-08-19 | PXD008184 | Pride
Pc-3 Pc-3/nkr Tmt labeling Prostate cancer 
TranscriptomicsDynamics of Virus-specific CD8+ T cells in the Human Nasal Cavity
The goal of this experiment is to compare the transcriptomic profile of CD8+ T cells isolated from the nasal cavity and whole blood at two different state, baseline and CD3/28 activated. This will allow us to characterise the unique features of CD8+ T cells in the nasal cavity. We isolated CD8+CD4...
ORGANISM(S): Homo sapiens 
2025-08-23 | E-MTAB-15436 | biostudies-arrayexpress
TranscriptomicsRNA-seq of group 1 Innate Lymphoid Cells (ILCs) in the mouse uterus and liver
We identified differences in the distribution of three group 1 ILC subsets in the mouse uterus. The dynamic distribution of g1 ILC subsets in the uterus at key stages of reproductive life may reflect subset-specific functions and emphasised the need for detailed characterisation of each subset
ORGANISM(S): Mus musculus 
2018-10-05 | E-MTAB-6812 | biostudies-arrayexpress
TranscriptomicsRNA-seq of primary mouse monocytes from miR-150 knockout and Tet3 knockout mice compared to wild type controls
Monocytes were isolated from blood of Wildtype, Mir150 and TET3 knockout mice, sorted for classical and non-classical monocyte subsets. RNA seq was performed on unstimulated monocytes.
ORGANISM(S): Mus musculus 
2018-10-26 | E-MTAB-7291 | biostudies-arrayexpress
TranscriptomicsRNA-seq expression profiling of humain MAIT cells in blood and liver as compared to mainstream TCD4+ and TCD8+ cells.
At variance with what is observed in mice, no distinct MAIT1 or MAIT17 subsets exist in human blood, as all MAIT cells express a variety of transcription factors such as Rorgt, Tbet, Eomes and Helios. However, they are also found in tissues in which they have specific effector functions. To determin...
ORGANISM(S): Homo sapiens 
2018-12-03 | E-MTAB-7143 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Group 2 innate lymphoid cells (ILC2) from uterine tissue (Virgin, E9.5, E18.5)
Group 2 innate lymphoid cells (ILC2) promote the production of a type-2 immunological environment in the uterus and have tissue-specific gene signatures that change with pregnancy.
ORGANISM(S): Mus musculus 
2023-04-15 | E-MTAB-5803 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Group 2 innate lymphoid cells (ILC2) from lung and lymph node
Group 2 innate lymphoid cells (ILC2) promote the production of a type-2 immunological environment in the uterus and have tissue-specific gene signatures that change with pregnancy.
ORGANISM(S): Mus musculus 
2023-04-15 | E-MTAB-5806 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse small intestinal CCR6+ group3 innate lymphoid cells
CCR6+NKp46- ILC3 were isolated from the small intestine of untreated mice by flow cytometry. ILC3 from 3 mice were pooled for subsequent RNA sequencing.
ORGANISM(S): Mus musculus 
2019-10-11 | E-MTAB-8387 | biostudies-arrayexpress
TranscriptomicsInflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis
Cholangitis mouse models were characterised by selective intrahepatic expansion of type 2 conventional dendritic cells, whereas plasmacytoid and type 1 conventional dendritic cells were not expanded. Expansion of type 2 conventional dendritic cells in human PSC lesions was confirmed by histology. De...
ORGANISM(S): Mus musculus 
2022-07-08 | E-MTAB-11821 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of aortic CD3+ T cells
We dissected the changes in the infiltrating T cell population in the aorta of cDC1-impaired mice compared with control mice in atheroprone Ldlr-/- mice by scRNAseq. To this aim, lethally irradiated Ldlr-/- CD45.1 mice were grafted with cDC1-impaired Xcr1Cre-DTA or control Xcr1Cre bone marrow (BM) a...
ORGANISM(S): Mus musculus 
2025-06-18 | E-MTAB-14540 | biostudies-arrayexpress
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