Sort   by:  
 Page size 
ProteomicsThe proteome of B cell maturation identifies PDCD4 as limiting the response of marginal zone B cells – WT and PDCD4 KO MZ B cells. Includes Fasta file
During B cell maturation, transitional and mature B cells acquire cell-intrinsic features that determine their ability to exit quiescence and mount effective immune responses. We used high-resolution mass spectrometry to quantify the proteome of B cell subsets from the mouse spleen and map the diffe...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-29 | PXD043351 | Pride
B cells Pdcd4 
ProteomicsThe proteome of B cell maturation identifies PDCD4 as limiting the response of marginal zone B cells – marginal zone B cells WT and PDCD4 KO
During B cell maturation, transitional and mature B cells acquire cell-intrinsic features that determine their ability to exit quiescence and mount effective immune responses. We used high-resolution mass spectrometry to quantify the proteome of B cell subsets from the mouse spleen and map the diffe...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-21 | PXD037563 | Pride
Immunology Pdcd4 B cells 
GenomicsPLK1-mediated PDCD4 degradation confers resistance to enzalutamide in prostate cancer
PLK1-mediated PDCD4 degradation confers resistance to enzalutamide in prostate cancer
PRJNA1183556 | ENA
ProteomicsIdentification of cellular proteins binding to the 3’UTR of Programmed Cell Death 4 mRNA
The aim of the project is to identify RNA-binding proteins (RBPs) that interact with the 3’ untranslated region (3’UTR) of the programmed cell death 4 (PDCD4) mRNA. PDCD4 is an inflammatory tumor suppressor gene. The translation of PDCD4 mRNA is regulated by multiple RBPs. The aim is to identify RBP...
ORGANISM(S): Homo sapiens (Human) 
2020-12-11 | PXD017376 | Pride
Mass spectrometry 3’ untranslated region Rna-protein interaction Programmed cell death 4 Rna-binding protein 
GenomicsNeuronal activity promotes nuclear proteasome-mediated degradation of PDCD4 to regulate activity-dependent transcription in neurons
Neuronal activity promotes nuclear proteasome-mediated degradation of PDCD4 to regulate activity-dependent transcription in neurons
PRJNA685031 | ENA
GenomicsFunctional characterisation of tumour suppressor PDCD4 reveals a previously undisclosed role in the control of cell adhesion
Functional characterisation of tumour suppressor PDCD4 reveals a previously undisclosed role in the control of cell adhesion
PRJNA1136977 | ENA
GenomicsFunctional characterisation of tumour suppressor PDCD4 reveals a previously undisclosed role in the control of cell adhesion
Functional characterisation of tumour suppressor PDCD4 reveals a previously undisclosed role in the control of cell adhesion
PRJNA1136976 | ENA
TranscriptomicsPLK1-mediated PDCD4 degradation confers resistance to enzalutamide in prostate cancer
Enzalutamide, a second-generation androgen receptor inhibitor, is utilized for treating patients with metastatic castration-resistant prostate cancer (mCRPC). However, acquired resistance to enzalutamide presents a significant clinical challenge, necessitating novel strategies for overcoming this re...
ORGANISM(S): Homo sapiens 
2025-04-16 | GSE281361 | GEO
GenomicsAnalysis of PDCD4 knockdown effects by high throughput sequencing of a human epithelial cell line
Analysis of PDCD4 knockdown effects by high throughput sequencing of a human epithelial cell line
PRJNA576260 | ENA
TranscriptomicsNeuronal activity promotes nuclear proteasome-mediated degradation of PDCD4 to regulate activity-dependent transcription in neurons
Activity-dependent gene expression is critical for synapse development and plasticity. To elucidate novel mechanisms linking neuronal activity to changes in transcription, we compared the nuclear proteomes of tetrodotoxin-silenced and bicuculline-stimulated cultured neurons using nuclear-localized A...
ORGANISM(S): Rattus norvegicus 
2020-12-15 | GSE163127 | GEO
Sort   by:  
 Page size