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ProteomicsUrinary glycopeptide analysis for the investigation of novel biomarkers
The aim of this study was to investigate the presence of intact O- and N-glycopeptides in profiles of normal human urine analyzed by capillary electrophoresis coupled to mass spectrometry (CE-MS).CE and liquid chromatography coupled to tandem mass spectrometry (CE- and LC-MS/MS) were both used to i...
ORGANISM(S): Homo sapiens (Human) 
2018-11-29 | PXD011214 | Pride
Glycosylation Glycopeptides Urine Posttranslational modifications Protein biomarkers 
ProteomicsPeptides in plasma, urine, and dialysate: towards unraveling renal peptide handling
We investigated the endogenous peptidomes of spent hemodialysate, urine, and plasma, to shed light on peptide handling in the kidney. Our study was based on the hypothesis that hemodialysis replaces glomerular filtration and aims at gaining first insight into the comparative distribution of the pept...
ORGANISM(S): Homo sapiens (Human) 
2020-07-31 | PXD019407 | Pride
Thymosin beta-4 Urine Clinical study Plasma Hemodialysis fluid 
ProteomicsUrine proteomics in IgA nephropathy
we aimed at developing a urinary biomarker-based algorithm that predicts rapid disease progression in IgAN, thus enabling a personalized risk stratification.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD020288 | Pride
Ckd Glomerulonephritis : iga Progression Igan Biomarker Urine proteomics 
ProteomicsUrinary peptides enable assessment of disease severity in COVID-19
In this article, we report first data on the urinary test COVID31 that enables prediction of critical progression and death outcomes in COVID-19 patients. COVID31 is composed of 31 endogenous peptides mainly derived from various collagen chains that enable differentiation of moderate and severe dise...
ORGANISM(S): Homo sapiens (Human) 
2020-09-28 | PXD020444 | Pride
Sars-cov-2 Covid31 Covid-19 Proteome 
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