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ProteomicsPeli1-mediated TSC1 ubiquitination site
Metabolic fitness of T cells is crucial for immune responses against infections and tumorigenesis. Both the T cell receptor (TCR) signal and environmental cues contribute to the induction of T cell metabolic reprogramming, but the underlying mechanism is incompletely understood. Here we identified t...
ORGANISM(S): Homo sapiens (Human) 
2020-11-23 | PXD020734 | Pride
Peli1  tsc1  ubiquitination 
ProteomicsPeli1 knock-out and wild type mouse brain proteomes during the disease course of experimental autoimmune encephalomyelitis
The ubiquitin ligase Peli1 has previously been suggested as a potential treatment target in multiple sclerosis since the knock-out induced less activated microglia and less inflammation in the CNS of experimental autoimmune encephalomyelitis in mice. In the present study the brain proteomes of Peli1...
ORGANISM(S): Mus musculus (Mouse) 
2016-09-27 | PXD003710 | Pride
Tmt Label-free Eae Cns Peli1 Multiple sclerosis Quantitative proteomics 
UnknownPeli1 signaling blockade attenuates congenital zika syndrome.
Not available
S-EPMC7297310 | biostudies-literature
UnknownPELI1 and EGFR cooperate to promote breast cancer metastasis.
Not available
S-EPMC9968314 | biostudies-literature
UnknownPeli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination.
Not available
S-EPMC12011377 | biostudies-literature
UnknownPeli1 Modulates the Subcellular Localization and Activity of Mdmx.
Not available
S-EPMC5984691 | biostudies-literature
UnknownPeli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation.
Not available
S-EPMC3899792 | biostudies-literature
UnknownPeli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
Not available
S-EPMC7561136 | biostudies-literature
UnknownThe ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Not available
S-EPMC8115645 | biostudies-literature
UnknownThe E3 Ubiquitin Ligase Peli1 Deficiency Promotes Atherosclerosis Progression.
Not available
S-EPMC9265341 | biostudies-literature
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