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ProteomicsThermal proteome profiling of MCF-7 breast cancer cell line
Palbociclib (Ibrance, Pfizer) is a recent drug approved by the FDA for phase 3 clinical trials in treating estrogen-receptor-positive and HER2-negative breast cancer. In vitro, palbociclib, a selective inhibitor of CDK4 and CDK6, was shown to reduce cellular proliferation of breast cancer cell lines...
ORGANISM(S): Homo sapiens (Human) 
2018-04-18 | PXD003704 | Pride
Lc-msms Drug discovery Thermal proteome Tmt Palbocilcib Quantitative proteomics 
Proteomicsanti-fungal effectors delivered by the Type VI secretion system - a proteomic analysis
Targeting a new kingdom: anti-fungal effectors delivered by the Type VI secretion system
ORGANISM(S): Candida albicans (Yeast) 
2018-05-17 | PXD006916 | Pride
Tmt-6plex Label-free Serratia marcescens Candida albicans Anti-fungal effectors Lc-msms 
ProteomicsLRRK2 signalling pathway in Mycobacterium tuberculosis
LRRK2 promotes Mycobacterium tuberculosis clearance by regulating phagosome maturation in mouse macrophages
ORGANISM(S): Mus musculus (Mouse) Mycobacterium tuberculosis 
2018-05-16 | PXD006909 | Pride
Lc-ms Lrrk2 Dimethyl labelling Phosphoproteomic Label-free Raw 264.1 Bmdms 
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