Sort   by:  
 Page size 
ProteomicsQuantitative proteomic and phosphoproteomic profiling of Sh3rf3-deficient ASD mouse model via 6Plex-TMT and phosphoproteomic
This study aims to systematically investigate the molecular mechanisms underlying autism spectrum disorder (ASD) by analyzing the proteome and phosphoproteome of a Sh3rf3-deficient mouse model. SH3RF3 (SH3 domain-containing RING finger protein 3) is implicated in synaptic regulation pathways, yet it...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD061722 | Pride
Prefrontal cortex Mouse Ms Sh3rf3 
ProteomicsMitochondrial proteomics of Mouse Brain and Liver
TMT 6Plex based quantitative Proteomics study of Mouse Liver and Brain mitochondria
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-05-22 | MSV000083837 | MassIVE
ProteomicsEvaluation of a Dual Isolation Width Acquisition (DIWA) method for isobaric labelling ratio decompression
Stable isotope labelling of peptides using isobaric reagents such as iTRAQ and TMT enables the multiplexed analysis of proteomes with deep quantitative coverage. Isobaric tagging demonstrates high precision but imperfect accuracy due to ratio underestimation caused by co-fragmentation of ions with m...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2019-01-07 | PXD010571 | Pride
Method development Tmt Msms Diwa 
ProteomicsPhospho- and total- proteomic analysis of FAK knockout in primary mouse lung endothelial cells
We assessed the impact of Endothelial Focal Adhesion kinase (ECFAK) knockout, using primary lung endothelial cells isolated (at P10-P14) from a FAK flox/flox mice crossed with mice expressing a tamoxifen-inducible Cre(iCreERT2) that is driven by endothelial cell (EC)-selective platelet-derived growt...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-13 | PXD030824 | Pride
Fak  endothelial cells  quantitative proteomics  vegf  tmt 
ProteomicsAntimycin A-treated vs ETFDH-ko myoblasts TMT
The electron transfer flavoprotein dehydrogenase (ETFDH) is the bottleneck enzyme of fatty acid oxidation (FAO). We performed a TMT 6plex analysis on Antimycin A treated and ETFDH-ko myoblasts (compared to CRL).
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD045588 | Pride
Myoblast Tmt Etfdh Antimycin a 
UnknownGlyphosate does not substitute for glycine in proteins of actively dividing mammalian cells.
Not available
S-EPMC6686468 | biostudies-literature
ProteomicsProteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy
Proteomics and bioinformatic analyses of hippocampus were performed. High-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with TMT-6plex quantification, was applied for global protein expression analysis. The proteomics results were validated by Wester...
ORGANISM(S): Homo sapiens (Human) 
2020-07-17 | PXD010544 | Pride
Temporal lobe epilepsy Proteomics Vesicle transmitters packaging Hippocampus sclerosis Annexin 
ProteomicsProteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy
Proteomics and bioinformatic analyses of hippocampus were performed. High-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with TMT-6plex quantification, was applied for global protein expression analysis. The proteomics results were validated by Wester...
ORGANISM(S): Homo sapiens (Human) 
2020-07-17 | PXD010543 | Pride
Temporal lobe epilepsy Proteomics Vesicle transmitters packaging Hippocampus sclerosis Annexin 
ProteomicsBreast ECM stiffness - CA1a cells
Comparision of CA1a cells grown in normal breast tissue pressure (NBP, 140 Pa) and breast tumor tissue pressure (BTP, 5000 Pa). Both conditions cultured in triplicates and quantified using TMT 6plex. TMT 126-128 - NBP TMT 129-131 - BTP
ORGANISM(S): Homo Sapiens (human) 
2024-11-15 | PXD030965 | JPOST Repository
ProteomicsTranscriptome-wide identification of coding and noncoding RNA-binding proteins defines the extended RNA interactome of Leishmania mexicana
Non-poly(A) RNA molecules including noncoding RNAs (ncRNAs) comprise the major portion of the total transcribed molecules in the cell. In addition to the mRNAs the ncRNAs also function as ribonucleoprotein particles (RNPs) and carry out biological functions including synthesis of new proteins, RNA p...
ORGANISM(S): Leishmania mexicana MHOM/GT/2001/U1103 
2022-01-14 | PXD028092 | Pride
Leishmania Rna-binding proteins 
Sort   by:  
 Page size