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ProteomicsA simplified perchloric acid workflow with neutralization (PCA-N) for democratizing deep plasma proteomics at population scale - Submission04
This project presents PCA-N, a novel plasma proteomics workflow that uses perchloric acid with neutralization to dramatically improve sample preparation efficiency. By eliminating solid-phase extraction and enabling 384-well plate compatibility, PCA-N reduces sample volume requirements to just 5 μL,...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD064487 | Pride
Lc-msms Plasma 
ProteomicsA simplified perchloric acid workflow with neutralization (PCA-N) for democratizing deep plasma proteomics at population scale - Submission 5
This project presents PCAᴺ, a novel plasma proteomics workflow that uses perchloric acid with neutralization to dramatically improve sample preparation efficiency. By eliminating solid-phase extraction and enabling 384-well plate compatibility, PCAᴺ reduces sample volume requirements to just 5 μL, c...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD064475 | Pride
Lc-msms Plasma 
ProteomicsUnveiling the unfolded proteome: evaluation and comparison of methods for the enrichment of intrinsically disordered proteins
Intrinsically disordered proteins (IDPs) comprise a significant fraction of the eukaryotic proteome and are characterised by the absence of stable secondary or tertiary structures under physiological conditions. Despite their functional importance, comprehensive proteomic analysis of IDPs remains a ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD070700 | Pride
Heat extraction Lc-ms Intrinsically disordered proteins Prefractionation methods Label-free quantification Perchloric acid extraction Disorder prediction algorithm Instrinsically disordered proteins enrichment 
UnknownAnalysis of Cyanogenic Compounds Derived from Mandelonitrile by Ultrasound-Assisted Extraction and High-Performance Liquid Chromatography in Rosaceae and Sambucus Families.
Not available
S-EPMC8705553 | biostudies-literature
ProteomicsQuantitative Analysis of Lysine Malonylation Proteome Unravels Physiological and Biochemical Mechanism in Responding to Salicylic Acid in Roots of Platycodon grandiflorus
Salicylic acid, as a plant hormone, significantly affects physiological and biochemical indexes of such as soluble sugar, malondialdehyde content, peroxidase and superoxide dismutase enzyme activity in Platycodon grandiflorus. Lysine malonylation is a post-translational modification that involves va...
ORGANISM(S): Platycodon grandiflorus 
2025-05-07 | PXD058676 | Pride
Platycodon grandiflorus  salicylic acid  lysine malonylation  medicinal plants  qualitative proteome  post-translational modification. 
TranscriptomicsH. salinarum NRC-1 vs VNG2099C knockout
To investigate the contribution of ribonucleases to post-transcriptional regulation of mRNA levels, we examined the fitness consequences and gene expression changes of ribonuclease mutants in the extreme halophilic archaeon Halobacterium salinarum NRC-1. H. salinarum NRC-1 is known to use a large re...
ORGANISM(S): Halobacterium sp. NRC-1 
2014-03-03 | E-GEOD-45988 | biostudies-arrayexpress
UnknownFirst HPLC-UV method for the determination of homocysteine thiolactone in human urine after derivatization with 1-benzyl-2-chloropyridinium bromide.
Not available
S-EPMC11873195 | biostudies-literature
UnknownEnrichment of Low-Abundance and Low-Molecular-Weight Proteins in Human Milk Using Mass Spectrometry-Based Proteomics.
Not available
S-EPMC12461359 | biostudies-literature
UnknownSimultaneous Quantification of Fumonisins and Their Hydrolyzed Metabolites in Donkey Matrices: A Tool for Exposure Assessment and Toxicokinetic Studies.
Not available
S-EPMC12944729 | biostudies-literature
UnknownLiquid Chromatographic Determination of Biogenic Amines in Fish Based on Pyrene Sulfonyl Chloride Pre-Column Derivatization.
Not available
S-EPMC7278825 | biostudies-literature
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